Atypical Lipomatous Tumor/Well Differentiated Liposarcoma

Preferred Label : Atypical Lipomatous Tumor/Well Differentiated Liposarcoma;

NCIt synonyms : Atypical Lipomatous Tumor; Atypical Lipoma; Well-Differentiated Liposarcoma; ALT/WDLPS; Well Differentiated Liposarcoma; ALT; Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma;

NCIt related terms : Liposarcoma, well differentiated; Liposarcoma, differentiated;

CISMeF acronym : ALT;

NCIt definition : A locally aggressive mesenchymal neoplasm composed either entirely or partly of an adipocytic proliferation showing at least focal nuclear atypia in both adipocytes and stromal cells. Atypical lipomatous tumor and well-differentiated liposarcoma are synonyms describing lesions that are morphologically and genetically identical. Amplification of MDM2 and/or CDK4 is almost always present. (WHO 2020);

Neoplastic status : Undetermined;

ICD-O code : 8850/1; 8851/3;

Details

Origin ID

C6505;

UMLS CUI

C1266129;

Automatic exact mappings (from CISMeF team)
- Atypical Lipoma [MeSH concept]
- Atypical lipomatous tumour [ICD-11 Extension code]
- L-alanine:2-oxoglutarate aminotransferase activity [GO term]
- Liposarcoma, well differentiated [ICD-O code]
- Liposarcoma, well differentiated [ICD-11 Extension code]
- Liposarcoma, well differentiated (morphologic abnormality) [SNOMED CT concept]
- Well Differentiated Liposarcoma [MeSH concept]
- Well-differentiated liposarcoma [ORDO Disease]
- alanine aminotransferase [Artificial nutrition thesaurus concept]
- alanine aminotransferase [COVID-19 Thesaurus concept]
- lipoma [MeSH Descriptor]
- lipoma, pleomorphic [MeSH concept]
- liposarcoma [MeSH Descriptor]
- liposarcoma, well differentiated [SNOMED Notion]
- well differentiated liposarcoma [Radlex concept]
Disease excludes normal cell origin
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Well-Circumscribed Lesion [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
False automatic mappings
- HIV Non-Progressors [MeSH Descriptor]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Atypical lipoma [ICD-O code]
- Atypical lipoma (morphologic abnormality) [SNOMED CT concept]
- atypical lipoma [Radlex concept]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_has_abnormal_cell
- Atypical Adipocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Lipocyte [NCIt concept]
- Neoplastic Mature Adipocyte [NCIt concept]
disease_has_finding
- Locally Aggressive Lesion [NCIt concept]
disease_has_normal_cell_origin
- Adipocyte [NCIt concept]
- Connective and Soft Tissue Cell [NCIt concept]
disease_has_normal_tissue_origin
- Adipose Tissue [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 1 [NCIt concept]
- Human Chromosome 12 [NCIt concept]
disease_mapped_to_gene
- MDM2 Gene [NCIt concept]
disease_may_have_abnormal_cell
- Monovacuolated Lipoblast [NCIt concept]
- Multivacuolated Lipoblast [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Giant Rod Chromosome [NCIt concept]
- Supernumerary Circular Chromosome [NCIt concept]
disease_may_have_molecular_abnormality
- CDK4 Gene Amplification [NCIt concept]
- MDM2 Gene Amplification [NCIt concept]
pathogenesis_of_disease_involves_gene
- MDM2 Gene [NCIt concept]
- MDM2 SNP309 Allele [NCIt concept]
- MDM2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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