Low Grade Central Osteosarcoma

Preferred Label : Low Grade Central Osteosarcoma;

NCIt synonyms : Intraosseous Well-Differentiated Osteosarcoma; Intraosseous Well-Differentiated Osteogenic Sarcoma; Low Grade Intramedullary Osteosarcoma; Low-Grade Intramedullary Osteosarcoma; LGCOS; Intraosseous Well Differentiated Osteosarcoma;

NCIt related terms : Low-grade central osteosarcoma;

NCIt definition : A low grade osteosarcoma arising from the medullary portion of the bone. It affects the long bones and is characterized by the presence of fibroblastic stroma and osteoid production. Pain and swelling are the usual sign and symptom. The prognosis is more favorable than conventional osteosarcoma.;

Neoplastic status : Malignant;

ICD-O code : 9187/3;

Details

Origin ID

C6474;

UMLS CUI

C1266163;

Automatic exact mappings (from CISMeF team)
- Intraosseous well differentiated osteosarcoma [ICD-11 Extension code]
- Low grade central osteosarcoma [ICD-11 Extension code]
- Low grade central osteosarcoma (morphologic abnormality) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Intraosseous well differentiated osteosarcoma [ICD-O code]
- Intraosseous well differentiated osteosarcoma (morphologic abnormality) [SNOMED CT concept]
Disease excludes normal cell origin
- Bone Marrow Stem Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Pain [NCIt concept]
- Pathologic Fracture [NCIt concept]
Excludes anatomical site(s)
- Soft Tissue [NCIt concept]
Has associated anatomic sites
- Bone [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Musculoskeletal System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Intraosseous well differentiated osteosarcoma [ICD-O code]
- Intraosseous well differentiated osteosarcoma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- High Grade Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Connective and Soft Tissue Cell [NCIt concept]
- Malignant Osteoblast [NCIt concept]
- Malignant Spindle-Shaped Osteoblast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Osteoblast [NCIt concept]
disease_has_finding
- Intraosseous Lesion [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Osseous Differentiation [NCIt concept]
- Osteoid Formation [NCIt concept]
- Primary Lesion [NCIt concept]
disease_has_grade
- Low Grade [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Osteoblast [NCIt concept]
disease_has_normal_tissue_origin
- Bone Tissue [NCIt concept]
- Connective Tissue [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Medullary Bone [NCIt concept]
disease_has_primary_anatomic_site
- Bone [NCIt concept]
disease_may_have_molecular_abnormality
- CDK4 Gene Amplification [NCIt concept]
- MDM2 Gene Amplification [NCIt concept]

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