Malignant Testicular Leydig Cell Tumor

Preferred Label : Malignant Testicular Leydig Cell Tumor;

NCIt synonyms : Testicular Malignant Leydig Cell Tumor;

NCIt definition : A Leydig cell tumor characterized by a large size, cellular atypia, high mitotic activity, vascular invasion and necrotic changes. The prognosis is usually poor.;

Neoplastic status : Malignant;

Details

Origin ID

C39942;

UMLS CUI

C1515288;

Automatic exact mappings (from CISMeF team)
- malignant testicular Leydig cell tumor [DO Concept]
DO Cross reference
- testicular Leydig cell tumor [DO Concept]
Disease excludes abnormal cell
- Neoplastic Germ Cell [NCIt concept]
- Neoplastic Sertoli Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
Disease may have findings
- Erectile Dysfunction [NCIt concept]
- Painless Testicular Mass [NCIt concept]
- Reinke Crystals Formation [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Reproductive System [NCIt concept]
- Testis [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- malignant testicular Leydig cell tumor [DO Concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Leydig Cell [NCIt concept]
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]
disease_has_finding
- Atypia [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Necrotic Change [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
disease_has_normal_cell_origin
- Leydig Cell [NCIt concept]
disease_has_normal_tissue_origin
- Testicular Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Male Reproductive System [NCIt concept]
- Testis [NCIt concept]
disease_may_have_associated_disease
- Gynecomastia [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 9 [NCIt concept]
- Gain of Chromosome X [NCIt concept]
- Loss of Chromosome 16 [NCIt concept]
- Loss of Chromosome 8 [NCIt concept]
disease_may_have_molecular_abnormality
- CDK4 Gene Amplification [NCIt concept]
- MDM2 Gene Amplification [NCIt concept]

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