NCIt definition : A rare, benign fibro-osseous neoplasm that usually affects the jaws and predominantly
arises in children and adolescents. It is characterized by prominent osteoid formation
rimmed by osteoblasts in a fibrotic stroma. Patients usually present with painless
jaw expansion that is associated with rapid growth and tooth displacement. Amplifications
of MDM2 and RASAL1 genes have been detected in some cases. Recurrences have been reported
in a minority of cases.;