Skin Atypical Lipomatous Tumor

Preferred Label : Skin Atypical Lipomatous Tumor;

NCIt synonyms : Skin Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma; Skin ALT/WDLPS; Skin Atypical Lipomatous Tumor/Well Differentiated Liposarcoma; Skin ALT;

NCIt definition : A rare, locally aggressive cutaneous mesenchymal neoplasm characterized by the presence of an adipocytic proliferation exhibiting at least focal nuclear atypia in both adipocytes and stromal cells. Amplification of MDM2 and/or CDK4 is almost always present.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1382930;

Détails

Origin ID

C170472;

UMLS CUI

C5418575;

Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Well-Circumscribed Lesion [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
- Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Atypical Adipocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Lipocyte [NCIt concept]
- Neoplastic Mature Adipocyte [NCIt concept]
disease_has_finding
- Cutaneous Involvement [NCIt concept]
- Locally Aggressive Lesion [NCIt concept]
- Superficial Lesion [NCIt concept]
disease_has_normal_cell_origin
- Adipocyte [NCIt concept]
- Connective and Soft Tissue Cell [NCIt concept]
disease_has_normal_tissue_origin
- Adipose Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Connective and Soft Tissue [NCIt concept]
- Dermis [NCIt concept]
- Skin [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 1 [NCIt concept]
- Human Chromosome 12 [NCIt concept]
disease_mapped_to_gene
- MDM2 Gene [NCIt concept]
disease_may_have_abnormal_cell
- Monovacuolated Lipoblast [NCIt concept]
- Multivacuolated Lipoblast [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Giant Rod Chromosome [NCIt concept]
- Supernumerary Circular Chromosome [NCIt concept]
disease_may_have_molecular_abnormality
- CDK4 Gene Amplification [NCIt concept]
- MDM2 Gene Amplification [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients