Insulin Receptor Substrate 4

Preferred Label : Insulin Receptor Substrate 4;

NCIt synonyms : IRS4; pp160; PY160; Phosphoprotein of 160 kDa; Insulin Receptor Substrate-4; 160 kDa Phosphotyrosine Protein; IRS-4;

NCIt definition : Insulin receptor substrate 4 (1257 aa, 134 kDa) is encoded by the human IRS4 gene. This protein plays a role in co-localization of receptor tyrosine kinases with SH2 domain-containing downstream signaling proteins.;

Details

Origin ID

C28476;

UMLS CUI

C2362594;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IRS4 protein, human [MeSH Supplementary Concept]
- IRS4 protein, human [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- IRS4 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- PTB Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Longevity Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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