MAP Kinase-Activating Death Domain Protein

Preferred Label : MAP Kinase-Activating Death Domain Protein;

NCIt synonyms : Differentially Expressed in Normal and Neoplastic Cells Protein; Insulinoma-Glucagonoma Protein 20; MADD Protein; MAP-Kinase Activating Death Domain-Containing Protein; MADD; Rab3 GDP/GTP Exchange Factor; Insulinoma Glucagonoma Clone 20;

NCIt definition : MAP kinase-activating death domain protein (1647 aa, 183 kDa) is encoded by the human MADD gene. This protein is involved in the regulation of both guanine nucleotide exchange and cellular proliferation.;

Details

Origin ID

C26479;

UMLS CUI

C1449072;

False automatic mappings
- Multiple acyl-coa dehydrogenase deficiency [OMIM Phenotype]
OMIM relation
- Map kinase-activating death domain [OMIM gene]
See also inter- (CISMeF)
- Multiple acyl-CoA dehydrogenase deficiency [ICD-11 More detail]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MADD protein, human [MeSH Supplementary Concept]
- MADD protein, human [MeSH concept]
gene_encodes_gene_product
- MADD Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Heart [NCIt concept]
- Ovary [NCIt concept]
- Testis [NCIt concept]
gene_product_has_biochemical_function
- Adaptor Signaling Protein [NCIt concept]
- Apoptosis Promoter [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Death Domain [NCIt concept]
- RGD Motif [NCIt concept]
gene_product_is_element_in_pathway
- TNFR1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Death Signaling Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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