RGD Motif - CISMeF

Preferred Label : RGD Motif;

NCIt synonyms : RGD Peptide; Arginine-Glycine-Aspartic Acid Cell Adhesion Domain; RGD; RGD Tripeptide Sequence; RGD Domain; RGD Cell Adhesion Domain;

NCIt definition : A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one-letter codes for arginine - glycine - aspartic acid. This motif can be found in proteins of the extracellular matrix and it is recognized by different members of the integrin family. The structure of the tenth type III module of fibronectin has shown that the RGD motif lies on a flexible loop.;

Details

Origin ID

C13288;

UMLS CUI

C0052350;

Automatic exact mappings (from CISMeF team)
- RGD ID [EDAM data]
- arginyl-glycyl-aspartic acid [MeSH Supplementary Concept]
- arginyl-glycyl-aspartyl-serine [MeSH Supplementary Concept]
- capping protein regulator and myosin 1 linker 2 [HGNC gene]
Currated CISMeF NLP mapping
- arginyl-glycyl-aspartic acid [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- arginyl-glycyl-aspartic acid [MeSH concept]
- arginyl-glycyl-aspartic acid [MeSH Supplementary Concept]
is_structural_domain_or_motif_of_gene_product
- Adhesion G Protein-Coupled Receptor A2 [NCIt concept]
- HIV TAT Protein [NCIt concept]
- Lactadherin [NCIt concept]
- MAP Kinase-Activating Death Domain Protein [NCIt concept]
- Osteopontin [NCIt concept]
- Protein Wnt-6 [NCIt concept]

Keyword's position in hierarchy(ies) :

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