Interleukin-13

Preferred Label : Interleukin-13;

NCIt synonyms : IL13; Interleukin 13;

NCIt related terms : IL-13;

NCIt definition : Interleukin-13 (146 aa, 16 kDa) is encoded by the human IL13 gene. This protein plays a role in the negative regulation of cytokine production and the positive regulation of B-cell proliferation.;

Alternative definition : NCI-GLOSS: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-13 is made by a type of T lymphocyte. It reduces inflammation by blocking production of cytokines by macrophages. It also increases the number and activity of B lymphocytes. IL-13 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. It is a type of cytokine.;

Codes from synonyms : CDR0000682070; CDR0000557291;

Details

Origin ID

C20515;

UMLS CUI

C3658037;

Automatic exact mappings (from CISMeF team)
- Interleukin 13 [OMIM gene]
- Interleukin 13 (substance) [SNOMED CT concept]
- Interleukin-13 level [MedDRA LLT]
- interleukin 13 [HGNC gene]
- interleukin-13 receptor binding [GO term]
Currated CISMeF NLP mapping
- Interleukin 13 [LOINC component]
- Interleukin-13 [FMA entity]
- Interleukin-13 [MeSH Descriptor]
- Interleukin-13 [MeSH concept]
OMIM relation
- Interleukin 13 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- IL13 protein, human [MeSH Supplementary Concept]
- IL13 protein, human [MeSH concept]
- Interleukin 13 [LOINC component]
- Interleukin 13 (substance) [SNOMED CT concept]
- Interleukin-13 [FMA entity]
- Interleukin-13 [MeSH concept]
- Interleukin-13 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
endogenous_product_related_to
- Recombinant Interleukin-13 [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL13 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Asthma Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Th2 Cytokine Gene Induction Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Asthma [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Differentiation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
is_target
- Anti-IL-4/IL-13 Combination Agent QBX258 [NCIt concept]
- Lebrikizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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