Recombinant Interleukin-13

Preferred Label : Recombinant Interleukin-13;

NCIt synonyms : Interleukin 13; IL-13; Therapeutic Interleukin-13;

NCIt definition : The recombinant analogue of an endogenous cytokine interleukin 13 with potential antineoplastic activity. Produced by lymphocytes and exhibiting a variety of functions, interleukin-13 (therapeutic) inhibits DNA synthesis and regulates inflammatory and immune responses. In animal models, this agent has been shown to kill tumor cells both directly and indirectly by activating the host immune system at the tumor site. (NCI04);

CAS number : 148157-34-0;

Details

Origin ID

C1489;

UMLS CUI

C1522557;

Automatic exact mappings (from CISMeF team)
- Interleukin 13 [OMIM gene]
- Interleukin-13 level [MedDRA LLT]
- interleukin 13 [HGNC gene]
- interleukin-13 receptor binding [GO term]
Currated CISMeF NLP mapping
- Interleukin 13 [LOINC component]
- Interleukin-13 [FMA entity]
- Interleukin-13 [MeSH Descriptor]
- Interleukin-13 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Interleukin 13 (substance) [SNOMED CT concept]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_related_to_endogenous_product
- Interleukin-13 [NCIt concept]

Keyword's position in hierarchy(ies) :

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