Lebrikizumab - CISMeF

Preferred Label : Lebrikizumab;

NCIt synonyms : Immunoglobulin G4, Anti-(Human Interleukin 13) (Human-Mouse Monoclonal MILR1444a Gamma-4-Chain), Disulfide with Human-Mouse Monoclonal MILR1444a Kappa-Chain, Dimer; Monoclonal Antibody TNX-650; Anti-IL-13 Humanized Monoclonal Antibody TNX-650; TNX-650;

NCIt definition : A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.;

UNII : U9JLP7V031;

CAS number : 953400-68-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 953400-68-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MILR1444A; PRO301444;

Details

Origin ID

C87767;

UMLS CUI

C2981360;

Automatic exact mappings (from CISMeF team)
- TNX-650 [MeSH concept]
Currated CISMeF NLP mapping
- lebrikizumab [MeSH concept]
- lebrikizumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- lebrikizumab [MeSH concept]
- lebrikizumab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Interleukin-13 [NCIt concept]

Keyword's position in hierarchy(ies) :

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