Protein PALS1 - CISMeF

Preferred Label : Protein PALS1;

NCIt synonyms : Protein Associated with Lin-7 1; MAGUK p55 Subfamily Member 5; PALS1; Membrane Palmitoylated Protein 5; MPP5;

NCIt definition : Protein PALS1 (675 aa, 77 kDa) is encoded by the human PALS1 gene. This protein is involved in membrane polarization and cell-cell junction formation in differentiating cells.;

NCIt note : Protein PALS1 interacts with SARS-CoV envelope protein E and may also interact with SARS-CoV-2 protein E. (UniProt);

Details

Origin ID

C179701;

UMLS CUI

C1570165;

Automatic exact mappings (from CISMeF team)
- Membrane protein, palmitoylated 5 [OMIM gene]
- Zw10 interactor, antisense [OMIM Phenotype]
- protein associated with LIN7 1, MAGUK p55 family member [ORDO Gene]
- protein associated with LIN7 1, MAGUK p55 family member [HGNC gene]
OMIM relation
- Membrane protein, palmitoylated 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MPP5 protein, human [MeSH Supplementary Concept]
- MPP5 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- PALS1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Tight Junction [NCIt concept]
- Zonula Adherens [NCIt concept]
gene_product_has_structural_domain_or_motif
- PDZ Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Tight Junction Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Cell Adhesion Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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