NCIt synonyms : APC; APC Protein; Deleted In Polyposis 2.5; Adenomatosis Polyposis Coli Tumor Suppressor; Protein APC; Protein Phosphatase 1, Regulatory Subunit 46;
NCIt definition : Adenomatous polyposis coli protein (2843 aa, 312 kDa) is encoded by the human APC
gene. This protein is involved in both tumor suppression and the inhibition of the
Wnt signaling pathway.;