RAS Family Oncogene

Preferred Label : RAS Family Oncogene;

NCIt synonyms : Oncogene RAS; RAS; Retrovirus Associated Sequence Oncogene; RAS Oncogene;

NCIt definition : A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten murine sarcoma viruses. Mutated or overexpressed forms of the human ras genes are associated with constitutive ras GTPase activity, increased cellular proliferation, and cell transformation.;

Details

Origin ID

C17061;

UMLS CUI

C0034678;

Currated CISMeF NLP mapping
- ras oncogene [MeSH concept]
False automatic mappings
- Rheumatoid arthritis [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- ras oncogene [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Tumorigenesis [NCIt concept]
is_target
- RAF Inhibitor BDTX-4933 [NCIt concept]
- RAS Inhibitor RMC-6236 [NCIt concept]
- RAS Peptide Cancer Vaccine TG01 [NCIt concept]
- Ras Inhibitor LUNA18 [NCIt concept]
- Ras Inhibitor RSC-1255 [NCIt concept]

Keyword's position in hierarchy(ies) :

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