26S ATP-Dependent Proteasome

Preferred Label : 26S ATP-Dependent Proteasome;

NCIt synonyms : 26S Proteasome Complex; 26S Proteosome; 26S ATP-Dependent Protease; 26S ATP-Dependent Proteasome; 26S Proteasome;

NCIt definition : Proteasomes are large multicatalytic proteolytic complexes found in all eukaryotic cells, and simpler forms have been found in archaebacteria and certain eubacteria. In eukaryotes, the 20S proteasome also exists as the central core of the 26S (2000 kDa) proteasome complex, which catalyzes the degradation of ubiquitin-conjugated proteins and contains an additional 19S complex, composed of regulatory proteins and six ATPases.;

Details

Origin ID

C13970;

UMLS CUI

C0286330;

Anatomic structure is physical part of
- Cell [NCIt concept]
Associated anatomy of gene products
- 26S Proteasome Complex Subunit SEM1 [NCIt concept]
- 26S Proteasome Non-ATPase Regulatory Subunit 10 [NCIt concept]
- 26S Proteasome Regulatory Subunit 6A [NCIt concept]
- 26S Proteasome Regulatory Subunit 7 [NCIt concept]
Automatic exact mappings (from CISMeF team)
- proteasome complex [GO term]
Contains anatomical structure(s)
- 20S Proteasome [NCIt concept]
- PA700 Regulatory Module [NCIt concept]
Currated CISMeF NLP mapping
- ATP dependent 26S protease [MeSH concept]
- ATP dependent 26S protease [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ATP dependent 26S protease [MeSH concept]
- ATP dependent 26S protease [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
is_target
- Copper Gluconate [NCIt concept]

Keyword's position in hierarchy(ies) :

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