Preferred Label : Copper Gluconate;
NCIt synonyms : Cupric Gluconate;
NCIt definition : The orally bioavailable copper salt of D-gluconic acid. In addition to its roles as
an enzyme cofactor for cytochrome C oxidase and superoxide dismutase, copper forms
complexes with the thiocarbamate disulfiram (DSF) forming DSF-copper complexes, which
enhances the DSF-mediated inhibition of the 26S proteasome; proteasome inhibition
may result in inhibition of cellular protein degradation, cessation of cell cycle
progression, inhibition of cellular proliferation, and the induction of apoptosis
in susceptible tumor cell populations.;
UNII : RV823G6G67;
InChIKey : OCUCCJIRFHNWBP-IYEMJOQQSA-L;
CAS number : 527-09-3;
Chemical formula : 2C6H11O7.Cu;
Origin ID : C80050;
UMLS CUI : C0009975;
Semantic type(s)
- concept_is_in_subset
- has_target
