GRB2-Associated-Binding Protein 1

Preferred Label : GRB2-Associated-Binding Protein 1;

NCIt synonyms : Growth Factor Receptor Bound Protein 2-Associated Protein; GRB2-Associated Binder 1; GAB1; GRB2-Associated Binding Protein 1; Growth Factor Receptor Bound Protein 2-Associated Protein 1;

NCIt definition : GRB2-associated-binding protein 1 (694 aa, 77 kDa) is encoded by the human GAB1 gene. This protein is involved in intracellular signaling from growth factor receptors.;

Details

Origin ID

C107456;

UMLS CUI

C1447432;

Automatic exact mappings (from CISMeF team)
- Grb2-associated binding protein 1 [OMIM gene]
OMIM relation
- Grb2-associated binding protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GAB1 protein, human [MeSH Supplementary Concept]
- GAB1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- GAB1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Signaling Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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