Protein Cereblon

Preferred Label : Protein Cereblon;

NCIt synonyms : CRBN;

NCIt definition : Protein cereblon (442 aa, 51 kDa) is encoded by the human CRBN gene. This protein plays a role in assembly and regulation of calcium-activated potassium channels in brain.;

Details

Origin ID

C104142;

UMLS CUI

C1611876;

OMIM relation
- Cereblon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CRBN protein, human [MeSH Supplementary Concept]
- CRBN protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CRBN Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_physical_part_of
- E3 Ubiquitin-Protein Transferase [NCIt concept]
gene_product_plays_role_in_biological_process
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]
is_target
- Avadomide [NCIt concept]
- Avadomide Hydrochloride [NCIt concept]
- BTK Degrader BGB-16673 [NCIt concept]
- BTK Degrader HSK29116 [NCIt concept]
- BTK Degrader NX-5948 [NCIt concept]
- CRL4-CRBN Modulator KPG-818 [NCIt concept]
- Cemsidomide [NCIt concept]
- Cereblon Modulator BTX-1188 [NCIt concept]
- Cereblon Modulator SP-3164 [NCIt concept]
- Cereblon Modulator TQB3820 [NCIt concept]
- Eragidomide [NCIt concept]
- GSPT1 MGD MRT-2359 [NCIt concept]
- Golcadomide [NCIt concept]
- Iberdomide Hydrochloride [NCIt concept]
- Mezigdomide [NCIt concept]
- Zelebrudomide [NCIt concept]

Keyword's position in hierarchy(ies) :

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