MeSH definition : A subtype of caspases that contain long pro-domain regions that regulate the activation
of the enzyme. The pro-domain regions contain protein-protein interaction motifs that
can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS;
DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated,
the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.;
A subtype of caspases that contain long pro-domain regions that regulate the activation
of the enzyme. The pro-domain regions contain protein-protein interaction motifs that
can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS;
DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated,
the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.