Preferred Label : genes, erbB-2;
MeSH definition : The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR,
ERBB-2), a protein with structural features similar to the epidermal growth factor
receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a
truncated form of the chicken erbB gene found in the avian erythroblastosis virus.
Overexpression and amplification of the gene is associated with a significant number
of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.;
MeSH synonym : c erbb 2 genes; c erbb 2 proto oncogenes; c-erbb-2 gene; c-erbb-2 genes; erbb 2 genes; erbb2 genes; gene, erbb2; genes, erbb2; genes, her2; her-2 gene; her-2 genes; her2 genes; neu gene; neu genes; her2 gene; erbb-2 genes; erbb-2 gene; c-erbb-2 proto-oncogenes; c-erbb-2 proto-oncogene; erbb2 gene; genes, her-2; genes, neu; gene, her2;
CISMeF synonym : erbB-2;
MeSH annotation : in titles & translations spell as erbB-2; GENES, ERBB-1 is also available;
Origin ID : D018734;
UMLS CUI : C0242957;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR,
ERBB-2), a protein with structural features similar to the epidermal growth factor
receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a
truncated form of the chicken erbB gene found in the avian erythroblastosis virus.
Overexpression and amplification of the gene is associated with a significant number
of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
