MeSH definition : Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus.
The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR)
whose kinase domain is constitutively activated by deletion of the ligand-binding
domain.;
MeSH synonym : oncogene products v erbb; oncogene proteins erbb; v erbb proteins; v-erbb proteins; erbb oncogene proteins; oncogene products v-erbb; oncogene proteins v erbB;
MeSH annotation : IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short
X ref; coordinate with specific virus;
Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus.
The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR)
whose kinase domain is constitutively activated by deletion of the ligand-binding
domain.