genes, erbb-1 - CISMeF

Preferred Label : genes, erbb-1;

MeSH definition : The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.;

MeSH synonym : erbb 1 genes; erbb-1 gene; erbb1 gene; erbb-1 genes; erbb1 genes; gene, erbb1; genes, erbb1;

CISMeF synonym : erbb-1;

MeSH hyponym : v-erbB genes; c-erbB-1 genes; v erbB Genes; v-erbB Gene; v-erbB Oncogenes; v erbB Oncogenes; v-erbB Oncogene; c erbB 1 Genes; c-erbB-1 Gene; EGFR Genes; Epidermal Growth Factor Receptor Genes; c-erbB-1 Proto-Oncogenes; c erbB 1 Proto Oncogenes; c-erbB-1 Proto-Oncogene; Genes, EGFR; EGFR Gene;

MeSH annotation : spell in titles & translations as erbB-1; GENES, ERBB-2 is also available;

Details

Origin ID

D018773;

UMLS CUI

C0242984;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Record concept(s)
- c-erbB-1 genes [MeSH concept]
- genes, erbB-1 [MeSH concept]
- v-erbB genes [MeSH concept]
See also
- ErbB Receptors [MeSH Descriptor]
- oncogene proteins v-erbb [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients