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Preferred Label : zinc fingers;

MeSH definition : Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.;

MeSH synonym : fingers, zinc; finger, zinc; motif, zinc finger; motifs, zinc finger; zinc finger motif; zinc finger; zinc finger motifs;

DeCS synonym : Zinc Finger DNA Binding Domains; Zinc Finger DNA-Binding Domains;

MeSH hyponym : Zinc Finger DNA Binding Domains;

Wikipedia link : https://en.wikipedia.org/wiki/Zinc finger;

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Keyword's position in hierarchy(ies) : arborescence

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Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.

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15/05/2024


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