PHD Finger Protein 20

Preferred Label : PHD Finger Protein 20;

NCIt synonyms : Glioma-Expressed Antigen 2; Hepatocellular Carcinoma-Associated Antigen 58; Novel Zinc Finger Protein; Transcription Factor TZP; PHF20;

NCIt definition : PHD finger protein 20 (1012 aa, 115 kDa) is encoded by the human PHF20 gene. This protein plays a role in the acetylation of histones and transcriptional regulation.;

NCIt note : PHD finger protein 20 may acetylate and stabilize cellular tumor antigen p53. (Nat Struct Mol Biol. 2012; 19:916-24 and J Biol Chem. 2012;2 87:11151-11163.);

Details

Origin ID

C106060;

UMLS CUI

C1448193;

Automatic exact mappings (from CISMeF team)
- PHD finger protein 20 [HGNC gene]
- Phd finger protein 20 [OMIM gene]
- zinc fingers [MeSH Descriptor]
OMIM relation
- Phd finger protein 20 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PHF20 protein, human [MeSH Supplementary Concept]
- PHF20 protein, human [MeSH concept]
gene_encodes_gene_product
- PHF20 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- AT Hook Motif [NCIt concept]
- C2H2 Zinc Finger [NCIt concept]
- PHD Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- Histone Acetylation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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