MeSH note : plays a role in limb and brain development; implicated in the transduction of SHH
signal; several mutations result in developmental defects of cranofacial and limb
structures; in particular the add (anterior digit-pattern deformity) and pdn (polydactyly
Nagoya) alleles; RefSeq NM_008130;
MeSH synonym : GLI-Kruppel family member GLI3 protein, mouse; polydactyly Nagoya protein, mouse; extra toes protein, mouse; anterior digit pattern deformity protein, mouse; brachyphalangy protein, mouse;