RNA-Binding protein EWS

Preferred Label : RNA-Binding protein EWS;

MeSH definition : A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS may play a role in neoplastic processes such as EWING SARCOMA.; A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.;

MeSH synonym : ews proto-oncogene protein; proto-oncogene protein, ews; ews, rna-binding protein; ews proto oncogene protein; ewing sarcoma breakpointregion 1 protein; ews protein; RNA binding protein EWS; EWSR1 Protein; Protein, EWSR1; Ewing Sarcoma Breakpoint Region 1 Protein; EWS RNA Binding Protein 1;

Is substance : O;

Details

Origin ID

D034802;

UMLS CUI

C0288194;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- RNA-Binding Protein EWS [NCIt concept]
Record concept(s)
- RNA-Binding protein EWS [MeSH concept]
Related MeSH Supplementary Concept(s)
- EWS-FLI fusion protein [MeSH Supplementary Concept]
- EWSR1 protein, human [MeSH Supplementary Concept]
- Ewsr1 protein, mouse [MeSH Supplementary Concept]
- Ewsr1a protein, zebrafish [MeSH Supplementary Concept]
- MTSF2 protein, Arabidopsis [MeSH Supplementary Concept]
See also
- zinc fingers [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients