polymerase chain reaction

Preferred Label : polymerase chain reaction;

MeSH definition : In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.;

MeSH synonym : polymerase chain reactions; reaction, polymerase chain; reactions, polymerase chain; pcr;

MeSH hyponym : nested polymerase chain reaction; inverse PCR; anchored PCR; PCR, Inverse; Inverse Polymerase Chain Reaction; Nested PCR; PCR, Nested; PCR, Anchored; Anchored Polymerase Chain Reaction;

Wikipedia link : https://en.wikipedia.org/wiki/Polymerase chain reaction;

Details

Origin ID

D016133;

UMLS CUI

C0032520;

Allowable qualifiers
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- ethics [MeSH Qualifier]
- history [MeSH Qualifier]
- instrumentation [MeSH Qualifier]
- methods [MeSH Qualifier]
- standards [MeSH Qualifier]
- statistics and numerical data [MeSH Qualifier]
- trends [MeSH Qualifier]
- veterinary [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Adamantinomatous Craniopharyngioma [NCIt concept]
- American College of Physicians [NCIt concept]
- C reactive protein [Artificial nutrition thesaurus concept]
- C reactive protein [COVID-19 Thesaurus concept]
- Cerebral palsy, ataxic, autosomal recessive [OMIM Phenotype]
- Complete Remission [NCIt concept]
- Cycloleucine [NCIt concept]
- Digital Polymerase Chain Reaction [NCIt concept]
- ISG15 wt Allele [NCIt concept]
- Nested PCR [NCIt concept]
- PCR Regimen [NCIt concept]
- PPARGC1B wt Allele [NCIt concept]
- Polymerase Chain Reaction [Blood Transfusion thesaurus concept]
- Polymerase chain reaction observation (finding) [SNOMED CT concept]
- Probe [LOINC method]
- Probe with target amplification technique (qualifier value) [SNOMED CT concept]
- Rapid amplification of complementary deoxyribonucleic acid ends [OMIConto structure]
- Virtual PCR [EDAM topic]
- polymerase chain reaction [OBI concept]
- polymerase chain reaction [IUPAC Term]
CISMeF manual mappings
- Polymerase chain reaction [OMIConto structure]
Currated CISMeF NLP mapping
- PCR [MedDRA LLT]
- Polymerase Chain Reaction [NCIt concept]
- Polymerase chain reaction [MedDRA Preferred Term]
- Polymerase chain reaction technique (qualifier value) [SNOMED CT concept]
False automatic mappings
- Pathologic Complete Response [NCIt concept]
- phosphocreatine [Substance BNPC]
- phosphocreatine [SNOMED Notion]
Indexing information
- spherical body protein 2, babesia bovis [MeSH Supplementary Concept]
- thy Pol-2 intein [MeSH Supplementary Concept]
- tli polymerase [MeSH Supplementary Concept]
- tth polymerase [MeSH Supplementary Concept]
Record concept(s)
- anchored PCR [MeSH concept]
- inverse PCR [MeSH concept]
- nested polymerase chain reaction [MeSH concept]
- polymerase chain reaction [MeSH concept]
See also
- ligase chain reaction [MeSH Descriptor]
- sequence tagged sites [MeSH Descriptor]
See also (suggested by CISMeF)
- reverse transcriptase polymerase chain reaction [MeSH Descriptor]
Semantic type(s)
- Molecular Biology Research Technique [UMLS semantic type]
UMLS correspondences (same concept)
- PCR [MedDRA LLT]
- Polymerase Chain Reaction [NCIt concept]
- Polymerase chain reaction [MedDRA Preferred Term]
- Polymerase chain reaction technique (qualifier value) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

Main resources

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