Polymerase Chain Reaction

Preferred Label : Polymerase Chain Reaction;

NCIt related terms : PCR;

NCIt definition : A method for amplifying a DNA base sequence using multiple rounds of heat denaturation of the DNA and annealing of oligonucleotide primers complementary to flanking regions in the presence of a heat-stable polymerase. This results in duplication of the targeted DNA region. Newly synthesized DNA strands can subsequently serve as additional templates for the same primer sequences, so that successive rounds of primer annealing, strand elongation, and dissociation produce rapid and highly specific amplification of the desired sequence. PCR also can be used to detect the existence of the defined sequence in a DNA sample.;

Alternative definition : NCI-GLOSS: A laboratory method used to make many copies of a specific DNA sequence.;

Codes from synonyms : CDR0000403140; CDR0000044798;

Details

Origin ID

C17003;

UMLS CUI

C0032520;

Automatic exact mappings (from CISMeF team)
- C reactive protein [Artificial nutrition thesaurus concept]
- C reactive protein [COVID-19 Thesaurus concept]
- Polymerase Chain Reaction [Blood Transfusion thesaurus concept]
- Probe [LOINC method]
- Probe with target amplification technique (qualifier value) [SNOMED CT concept]
- Virtual PCR [EDAM topic]
- polymerase chain reaction [OBI concept]
CISMeF manual mappings
- Polymerase chain reaction [OMIConto structure]
Currated CISMeF NLP mapping
- PCR [MedDRA LLT]
- Polymerase chain reaction [MedDRA Preferred Term]
- polymerase chain reaction [MeSH Descriptor]
- polymerase chain reaction [MeSH concept]
False automatic mappings
- Polymerase chain reaction technique (qualifier value) [SNOMED CT concept]
- phosphocreatine [MeSH Descriptor]
- phosphocreatine [MeSH concept]
- phosphocreatine [Substance BNPC]
- phosphocreatine [SNOMED Notion]
- polymerase chain reaction [IUPAC Term]
Semantic type(s)
- Molecular Biology Research Technique [UMLS semantic type]
UMLS correspondences (same concept)
- PCR [MedDRA LLT]
- Polymerase chain reaction [MedDRA Preferred Term]
- Polymerase chain reaction technique (qualifier value) [SNOMED CT concept]
- polymerase chain reaction [MeSH concept]
- polymerase chain reaction [MeSH Descriptor]
concept_is_in_subset
- CDISC SDTM Method Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Intervention Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- EWS Authorized Value Terminology [NCIt concept]
- EWS Molecular Analysis Table [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HL Authorized Value Terminology [NCIt concept]
- HL Lab Table [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- OS Authorized Value Terminology [NCIt concept]
- OS Molecular Analysis Table [NCIt concept]
- SeroNet Authorized Values [NCIt concept]
- SeroNet Study Descriptors [NCIt concept]

Keyword's position in hierarchy(ies) :

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