Post-Transplant Lymphoproliferative Disorder

Preferred Label : Post-Transplant Lymphoproliferative Disorder;

NCIt related terms : PTLD, NOS; Post transplant lymphoproliferative disorder, NOS; PTLD; Post-transplant lymphoproliferative disorder (PTLD);

NCIt definition : Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV- negative lymphomas of predominantly B-cell or less often T-cell type. (WHO, 2001);

Alternative definition : NCI-GLOSS: A condition in which a group of B-cells grow out of control after an organ transplant in patients with weakened immune systems. This usually happens if the patient has also been infected with Epstein-Barr virus. Post-transplant lymphoproliferative disorder may progress to non-Hodgkin lymphoma.; NICHD: Abnormal proliferation of B lymphocytes as a complication of immunosuppression occurring after solid organ or allogenic stem cell transplantation.;

ICD-O code : 9971/1;

Codes from synonyms : CDR0000512811; CDR0000468786; D47.Z1;

Details

Origin ID

C4727;

UMLS CUI

C0432487;

Automatic exact mappings (from CISMeF team)
- Immunodeficiency-associated lymphoproliferative disorders [ICD-11 Category]
- Post transplant lymphoproliferative disorder, NOS [ICD-11 Extension code]
- Post transplant lymphoproliferative disorder, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- Post-transplantation lymphoproliferation (morphologic abnormality) [SNOMED CT concept]
- Posttransplant lymphoproliferative disorder [PASCAL descriptor]
Currated CISMeF NLP mapping
- Lymphoproliferative disorder following transplantation (disorder) [SNOMED CT concept]
- Post transplant lymphoproliferative disorder [MedDRA Preferred Term]
- Post-transplant lymphoproliferative disease [ORDO Disease]
- post transplant lymphoproliferative disorder [Disease (Nov.)]
- post-transplant lymphoproliferative disorder [Radlex concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
Disease may have findings
- Extranodal Disease [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Lymphoproliferative disorder following transplantation (disorder) [SNOMED CT concept]
- Post transplant lymphoproliferative disorder [MedDRA Preferred Term]
- Post transplant lymphoproliferative disorder, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- Post-transplant lymphoproliferative disease [ORDO Disease]
- Post-transplant lymphoproliferative disorder (PTLD) [ICD-9 code]
- Post-transplantation lymphoproliferation (morphologic abnormality) [SNOMED CT concept]
- post transplant lymphoproliferative disorder [Disease (Nov.)]
- post-transplant lymphoproliferative disorder [Radlex concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
disease_has_finding
- Immunodeficiency [NCIt concept]
- Immunosuppression-Related Post-Transplant Toxicity [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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