renin-angiotensin system

Preferred Label : renin-angiotensin system;

MeSH definition : A BLOOD PRESSURE regulating system of interacting components that include RENIN; ANGIOTENSINOGEN; ANGIOTENSIN CONVERTING ENZYME; ANGIOTENSIN I; ANGIOTENSIN II; and angiotensinase. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming ANGIOTENSIN I. Angiotensin-converting enzyme, contained in the lung, acts on angiotensin I in the plasma converting it to ANGIOTENSIN II, an extremely powerful vasoconstrictor. Angiotensin II causes contraction of the arteriolar and renal VASCULAR SMOOTH MUSCLE, leading to retention of salt and water in the KIDNEY and increased arterial blood pressure. In addition, angiotensin II stimulates the release of ALDOSTERONE from the ADRENAL CORTEX, which in turn also increases salt and water retention in the kidney. Angiotensin-converting enzyme also breaks down BRADYKININ, a powerful vasodilator and component of the KALLIKREIN-KININ SYSTEM.;

MeSH synonym : system, renin-angiotensin; renin angiotensin system;

Wikipedia automatic translation : Renin–angiotensin system;

MeSH Hyperonym : Renin-Angiotensin-Aldosterone system; Renin Angiotensin Aldosterone System; System, Renin-Angiotensin-Aldosterone;

MeSH annotation : note X ref but do not index under ALDOSTERONE unless particularly discussed; DF: RA SYSTEM; note entry term but do not index under ALDOSTERONE unless particularly discussed;

Wikipedia link : https://en.wikipedia.org/wiki/Renin–angiotensin system;

Details

Origin ID

D012084;

UMLS CUI

C0035096;

ATC code(s)
- other agents acting on the renin-angiotensin system [ATC Code]
Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- MSR1 wt Allele [NCIt concept]
- No abnormality detected (finding) [SNOMED CT concept]
- Oncogene protein P21, RAS (substance) [SNOMED CT concept]
- Renin-Angiotensin Pathway [NCIt concept]
- Renin-angiotensin system [FMA entity]
- Shave [NCIt concept]
- Shaving [ICNP action]
- nothing to report [SYNODOS term]
- renin-angiotensin system [UBERON concept]
- renin–angiotensin–aldosterone system [COVID-19 Thesaurus concept]
- staphylococcus aureus [SNOMED Notion]
Record concept(s)
- Renin-Angiotensin system [MeSH concept]
- Renin-Angiotensin-Aldosterone system [MeSH concept]
See also
- aldosterone [MeSH Descriptor]
- angiotensin II [MeSH Descriptor]
- angiotensin-converting enzyme inhibitors [MeSH Descriptor]
- angiotensins [MeSH Descriptor]
- kallikrein-kinin system [MeSH Descriptor]
Semantic type(s)
- Body System [UMLS semantic type]
UMLS correspondences (same concept)
- Renin-angiotensin system [FMA entity]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients