Preferred Label : renin-angiotensin system;
Uberon definition : A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin,
an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced
by the liver, forming angiotensin I. The converting enzyme contained in the lung acts
on angiotensin I in the plasma converting it to angiotensin II, the most powerful
directly pressor substance known. It causes contraction of the arteriolar smooth muscle
and has other indirect actions mediated through the adrenal cortex.;
Uberon related term : renin-angiotensin system; renin angiotensin aldosterone system; renin-angiotensin-aldosterone system; renin angiotensin system;
Origin ID : 0018229;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- part of
A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin,
an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced
by the liver, forming angiotensin I. The converting enzyme contained in the lung acts
on angiotensin I in the plasma converting it to angiotensin II, the most powerful
directly pressor substance known. It causes contraction of the arteriolar smooth muscle
and has other indirect actions mediated through the adrenal cortex.
