Phosphofructokinase-1

Preferred Label : Phosphofructokinase-1;

MeSH definition : An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.;

MeSH synonym : 6-phosphofructokinase; 6-phosphofructo-1-kinase; fructose-6-p 1-kinase; fructose-6-phosphate 1-phosphotransferase; 6 phosphofructokinase; phosphofructokinase 1;

MeSH CAS label : ATP:D-fructose-6-phosphate 1-phosphotransferase;

MeSH Related Number : 9001-80-3 (CAS RN);

Registry Number MeSH : EC 2.7.1.11;

MeSH annotation : GEN or unspecified; prefer specifics; general or unspecified; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Phosphofructokinase-1;

Is substance : O;

UNII : EC 2.7.1.11;

Details

Origin ID

D010732;

UMLS CUI

C0031651;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 1-phosphofructokinase [SNOMED Notion]
- 1-phosphofructokinase (substance) [SNOMED CT concept]
- 1-phosphofructokinase activity [GO term]
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- 6-Phosphofructokinase, Muscle Type [NCIt concept]
- 6-phosphofructokinase [SNOMED Notion]
- 6-phosphofructokinase (substance) [SNOMED CT concept]
- Aurora Kinase C [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Pyrophosphate-fructose-6-phosphate 1-phosphotransferase (substance) [SNOMED CT concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
Indexing information
- 1,1-hydroxyoctanodiphosphonate [MeSH Supplementary Concept]
- phosphofructokinase regulatory factors [MeSH Supplementary Concept]
- ptms protein, rat [MeSH Supplementary Concept]
Record concept(s)
- Phosphofructokinase-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-phosphofructokinase [MeSH Supplementary Concept]
- phosphofructokinase regulatory subunit [MeSH Supplementary Concept]
See also
- Phosphofructokinase-2 [MeSH Descriptor]
- glycogen storage disease type vii [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 6-phosphofructokinase [SNOMED Notion]
- 6-phosphofructokinase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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