epilepsy, tonic-clonic

Preferred Label : epilepsy, tonic-clonic;

MeSH definition : A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329);

MeSH synonym : seizure disorder, tonic clonic; seizure disorders, tonic-clonic; tonic clonic convulsions; seizure syndromes, tonic-clonic; tonic clonic seizure syndrome; convulsions, tonic clonic; disorders, tonic-clonic convulsion; tonic-clonic seizure disorder; tonic-clonic convulsion syndromes; tonic-clonic epilepsy; tonic-clonic seizure syndrome; grand mal epilepsy; disorder, tonic-clonic convulsion; convulsion, grand mal; epilepsies, tonic-clonic; seizure disorder, major motor; syndromes, tonic-clonic convulsion; epilepsy, grand mal; syndromes, tonic-clonic seizure; convulsion syndromes, tonic-clonic; tonic clonic seizure disorder; tonic-clonic seizure syndromes; major epilepsies; tonic clonic convulsion disorder; major epilepsy; epilepsy, major; tonic clonic convulsion syndrome; seizure disorder, grand mal; syndrome, tonic-clonic seizure; seizure syndrome, tonic-clonic; tonic-clonic convulsion syndrome; tonic-clonic convulsion disorders; convulsion syndrome, tonic-clonic; convulsion disorders, tonic-clonic; major motor seizure disorder; convulsion, tonic clonic; tonic clonic convulsion; tonic-clonic convulsion disorder; convulsion disorder, tonic-clonic; tonic-clonic epilepsies; grand mal seizure disorder; grand mal convulsion; grand mal convulsions; syndrome, tonic-clonic convulsion; disorder, tonic-clonic seizure; disorders, tonic-clonic seizure; seizure disorder, tonic-clonic; tonic-clonic seizure disorders; convulsions, grand mal; epilepsy, tonic clonic;

MeSH hyponym : cryptogenic Tonic-Clonic epilepsy; epilepsy, Tonic-Clonic, familial; epilepsy, Tonic-Clonic, symptomatic; Symptomatic Tonic-Clonic Epilepsy; Epilepsies, Symptomatic Tonic-Clonic; Epilepsy, Symptomatic Tonic-Clonic; Symptomatic Tonic Clonic Epilepsy; Symptomatic Tonic-Clonic Epilepsies; Tonic-Clonic Epilepsies, Symptomatic; Tonic-Clonic Epilepsy, Symptomatic; Cryptogenic Tonic Clonic Epilepsy; Cryptogenic Tonic-Clonic Epilepsies; Epilepsies, Cryptogenic Tonic-Clonic; Epilepsy, Cryptogenic Tonic-Clonic; Tonic-Clonic Epilepsies, Cryptogenic; Tonic-Clonic Epilepsy, Cryptogenic; Epilepsy, Tonic-Clonic, Cryptogenic; Familial Tonic-Clonic Epilepsy; Epilepsies, Familial Tonic-Clonic; Epilepsy, Familial Tonic-Clonic; Familial Tonic Clonic Epilepsy; Familial Tonic-Clonic Epilepsies; Tonic-Clonic Epilepsies, Familial; Tonic-Clonic Epilepsy, Familial;

MeSH annotation : do not confuse with EPILEPSY, TONIC see EPILEPSY, GENERALIZED;

Details

Origin ID

D004830;

UMLS CUI

C0014549;

Allowable qualifiers
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemically induced [MeSH Qualifier]
- classification [MeSH Qualifier]
- complications [MeSH Qualifier]
- congenital [MeSH Qualifier]
- diagnosis [MeSH Qualifier]
- diagnostic imaging [MeSH Qualifier]
- diet therapy [MeSH Qualifier]
- drug therapy [MeSH Qualifier]
- economics [MeSH Qualifier]
- embryology [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- epidemiology [MeSH Qualifier]
- ethnology [MeSH Qualifier]
- etiology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- mortality [MeSH Qualifier]
- nursing [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiopathology [MeSH Qualifier]
- prevention and control [MeSH Qualifier]
- psychology [MeSH Qualifier]
- radiotherapy [MeSH Qualifier]
- rehabilitation [MeSH Qualifier]
- surgery [MeSH Qualifier]
- therapy [MeSH Qualifier]
- urine [MeSH Qualifier]
- veterinary [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CONVULSIONS GRAND MAL [WHO-ART Preferred Term]
- Clonic-tonic convulsions [MedDRA LLT]
- Convulsion grand mal [MedDRA LLT]
- Convulsions grand mal [MedDRA LLT]
- Epilepsy [ICPC-2 Rubric]
- Grand mal convulsion [MedDRA LLT]
- TONIC/ CLONIC CONVULSIONS [WHO-ART Included Term]
- Tonic clonic jerking [MedDRA LLT]
- Tonic-clonic convulsion [MedDRA LLT]
- Tonic-clonic epilepsy [MedDRA LLT]
- Tonic-clonic seizure (finding) [SNOMED CT concept]
- Tonic-clonic seizures [MedDRA LLT]
- Tonic/ clonic convulsions [MedDRA LLT]
- epilepsy with generalized tonic-clonic seizures [DO Concept]
Currated CISMeF NLP mapping
- Bilateral tonic-clonic seizure [HPO term]
- Epilepsy grand mal [MedDRA LLT]
- FITS NOS [WHO-ART Included Term]
- Generalised tonic-clonic seizure [MedDRA Preferred Term]
- Generalised tonic-clonic seizures [MedDRA High Level Term]
- Generalized tonic-clonic seizure [MedDRA LLT]
- Generalized tonic-clonic seizures (often develop in adolescence) [HPO term]
- Grand mal [PASCAL descriptor]
- Grand mal [MedDRA LLT]
- Grand mal epilepsy [MedDRA LLT]
- Grand mal seizure [MedDRA LLT]
- Grand mal seizure (finding) [Inactive SNOMED CT concept]
- Seizure grand mal [MedDRA LLT]
- Tonic-Clonic Epilepsy [NCIt concept]
- Tonic-Clonic Seizure [NCIt concept]
- Tonic-clonic epilepsy (disorder) [SNOMED CT concept]
- grand mal [SNOMED Notion]
- grand mal epilepsy [Disease (Nov.)]
DO Cross reference
- epilepsy with generalized tonic-clonic seizures [DO Concept]
Manual BTNT mappings - CISMeF
- primary generalized tonic-clonic seizures [Indication]
Record concept(s)
- cryptogenic Tonic-Clonic epilepsy [MeSH concept]
- epilepsy, Tonic-Clonic [MeSH concept]
- epilepsy, Tonic-Clonic, familial [MeSH concept]
- epilepsy, Tonic-Clonic, symptomatic [MeSH concept]
Related MeSH Supplementary Concept(s)
- epilepsy, intractable childhood, with generalized Tonic-Clonic seizures [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- epilepsy, generalized [MeSH Descriptor]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- CONVULSIONS GRAND MAL [WHO-ART Preferred Term]
- Clonic-tonic convulsions [MedDRA LLT]
- Convulsion grand mal [MedDRA LLT]
- Convulsions grand mal [MedDRA LLT]
- Epilepsy grand mal [MedDRA LLT]
- FITS NOS [WHO-ART Included Term]
- Grand mal [MedDRA LLT]
- Grand mal convulsion [MedDRA LLT]
- Grand mal epilepsy [MedDRA LLT]
- Major convulsion [MedDRA LLT]
- TONIC/ CLONIC CONVULSIONS [WHO-ART Included Term]
- Tonic-Clonic Epilepsy [NCIt concept]
- Tonic-clonic convulsion [MedDRA LLT]
- Tonic-clonic epilepsy [MedDRA LLT]
- Tonic-clonic epilepsy (disorder) [SNOMED CT concept]
- Tonic/ clonic convulsions [MedDRA LLT]
- epilepsy with generalized tonic-clonic seizures [DO Concept]
- grand mal [SNOMED Notion]

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