Preferred Label : phenobarbital;

MeSH definition : A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.;

MeSH synonym : phenylbarbital; phenemal; phenobarbitone; acid, phenylethylbarbituric; phenylethylbarbituric acid;

CISMeF synonym : 57-30-7 (Phenobarbital sodium);

MeSH hyponym : luminal; gardenal; Phenobarbital Sodium; hysteps; Sodium, Phenobarbital; Phenobarbital, Monosodium Salt; Monosodium Salt Phenobarbital;

MeSH CAS label : 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-;

MeSH Related Number : phenobarbital sodium; 50-06-6 (Phenobarbital); 57-30-7 (mono-Na salt); SW9M9BB5K3;

Registry Number MeSH : 50-06-6;

Related CAS MeSH : SW9M9BB5K3 (Phenobarbital sodium);

Wikipedia link : https://en.wikipedia.org/wiki/Phenobarbital;

Codes EINECS : 200-007-0;

Is substance : O;

UNII : YQE403BP4D;

InChIKey : DDBREPKUVSBGFI-UHFFFAOYSA-N;

Details


Main resources

You can consult :

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

https://www.cochrane.org/fr/CD001691/NEONATAL_quels-sont-les-benefices-et-les-risques-du-phenobarbital-pour-prevenir-les-hemorragies-cerebrales
2023
false
United Kingdom
France
French
meta-analysis
phenobarbital
infant, premature
intracranial hemorrhages
perinatal intraventricular hemorrhage
infant, newborn
treatment outcome
french abstract

---
https://www.has-sante.fr/jcms/p_3477473/fr/hot-axios
2023
France
health technology assessment
electrocoagulation
phenobarbital
Implant Dosage Form
Drug Delivery System Category
Implant Device Component
Device System
Implant Dosing Unit
Drug Delivery System
implant, nos
Electrocauterization
Implant
Mathematical Operator
prostheses and implants
Implant Dosage Form Category
Administration via Implantation
lumen of body system, nos

---
https://www.has-sante.fr/jcms/p_3321828/fr/hot-axios
2022
France
health technology assessment
prostheses and implants
lumen of body system, nos
electrocoagulation
phenobarbital
implant, nos

---
https://www.has-sante.fr/jcms/p_3276392/fr/hot-axios
2021
France
health technology assessment
electrocoagulation
phenobarbital
prostheses and implants
lumen of body system, nos
implant, nos

---
https://www.cochrane.org/fr/CD002217/phenobarbitone-contre-phenytoine-en-monotherapie-traitement-par-un-seul-medicament-pour-lepilepsie
2019
false
United Kingdom
France
French
meta-analysis
seizures
treatment outcome
phenobarbital
phenytoin
epilepsies, partial
anticonvulsants
epilepsy, tonic-clonic
french abstract

---
https://pharmacomedicale.org/medicaments/par-specialites/item/phenobarbital
2017
false
true
false
France
phenobarbital
phenobarbital
anticonvulsants
anticonvulsants
anticonvulsants
excitatory amino acid antagonists
GABA modulators
epilepsy
drug interactions
drug information
phenobarbital

---
http://www.has-sante.fr/portail/jcms/c_2732008/fr/kaneuron
2016
false
false
false
France
French
evaluation of the transparency committee
phenobarbital

---
http://www.lecrat.eu/?s=Etat+des+connaissances+sur+le+ph%C3%A9nobarbital
France
drug information
knowledge
phenobarbital
pregnancy, high-risk
teratogens
pregnancy, nos

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60323481
2012
France
summary of product characteristics
package leaflet
tablets
phenobarbital

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65328906
2012
France
summary of product characteristics
package leaflet
ophthalmic solutions
phenobarbital
gout

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61720831
2012
France
summary of product characteristics
package leaflet
phenobarbital
tablets

---
http://www.has-sante.fr/portail/display.jsp?id=c_461066
http://www.has-sante.fr/portail/jcms/c_1109523/kaneuron
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-11/kaneuron_19-10-2011_avis_ct-11248.pdf
2011
France
French
evaluation of the transparency committee
adult
child
epilepsy, generalized
epilepsies, partial
phenobarbital
anticonvulsants
pharmaceutical solutions
administration, oral
phenobarbital
insurance, health, reimbursement

---
http://www.has-sante.fr/portail/display.jsp?id=c_460632
http://www.has-sante.fr/portail/jcms/c_1109130/gardenal
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/gardenal_19-10-2011_avis_10954.pdf
2011
France
French
phenobarbital
anticonvulsants
administration, oral
injections
phenobarbital
insurance, health, reimbursement
adult
child
epilepsies, partial
epilepsy, generalized
status epilepticus
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/jcms/c_1118582/aparoxal
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-11/aparoxal_19-10-2011_avis_ct-11034.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_455070
2011
France
French
tablets
phenobarbital
phenobarbital
anticonvulsants
administration, oral
insurance, health, reimbursement
drug therapy, combination
epilepsy, generalized
epilepsies, partial
adult
child
evaluation of the transparency committee

---
http://www.cochrane.org/fr/CD000164
2011
false
true
false
United Kingdom
France
cerebral hemorrhage
pregnancy
infant, newborn
treatment outcome
review of literature
french abstract
phenobarbital
obstetric labor, premature

---
http://www.has-sante.fr/portail/display.jsp?id=c_458261
http://www.has-sante.fr/portail/jcms/c_1108557/alepsal
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/alepsal_19-10-2011_avis_10966.pdf
2011
France
French
drug combinations
administration, oral
phenobarbital
caffeine
anticonvulsants
adult
child
insurance, health, reimbursement
drug therapy, combination
epilepsies, partial
epilepsy, generalized
antiepileptics
evaluation of the transparency committee

---
http://www.aboutkidshealth.ca/en/healthaz/drugs/pages/phenobarbital.aspx?k=ph%c3%a9nobarbital;+%c3%a9pilepsie;+crises
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Phenobarbital.aspx
2010
Canada
English
French
phenobarbital
child
phenobarbital
administration, oral
injections
anticonvulsants
anticonvulsants
phenobarbital
drug information
patient education handout

---
http://www.lecrat.eu/?s=Ph%C3%A9nobarbital
2009
France
French
pregnancy
phenobarbital
anticonvulsants
phenobarbital
phenobarbital
drug information

---
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15/05/2024


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