Preferred Label : Lamotrigine;

MeSH definition : A phenyltriazine compound, sodium and calcium channel blocker that is used for the treatment of SEIZURES and BIPOLAR DISORDER.;

MeSH synonym : 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine; 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine;

MeSH hyponym : BW 430C; BW430C;

MeSH CAS label : 1,2,4-Triazine-3,5-diamine, 6-(2,3-dichlorophenyl)-;

MeSH Related Number : 84057-84-1 (Lamotrigine);

UNII : U3H27498KS;

Details


Main resources

You can consult :

A phenyltriazine compound, sodium and calcium channel blocker that is used for the treatment of SEIZURES and BIPOLAR DISORDER.

https://ansm.sante.fr/informations-de-securite/lamotrigine-lamictal-et-generiques-rappel-du-bon-usage-afin-de-limiter-le-risque-deruption-cutanee-grave-en-particulier-au-debut-du-traitement
2023
false
false
false
France
French
pharmacovigilance note
guidelines for drug use
Lamotrigine
Lamotrigine
risk management
lamotrigine
anticonvulsants
anticonvulsants
stevens-johnson syndrome
drug eruptions
Drug-Related side effects and adverse reactions
epidermal necrolysis, toxic
drug hypersensitivity syndrome
adult
child
drug interactions

---
https://ansm.sante.fr/actualites/lamotrigine-attention-au-risque-deruption-cutanee-grave-en-particulier-au-debut-du-traitement
2023
false
false
false
France
French
pharmacovigilance note
Lamotrigine
lamotrigine
drug eruptions
administration, oral
anticonvulsants
antipsychotic agents
drug hypersensitivity syndrome
epidermal necrolysis, toxic
Drug-Induced stevens johnson syndrome
guidelines for drug use

---
https://www.has-sante.fr/jcms/p_3322081/fr/lamictal-lamotrigine-epilepsies-partielles-et-generalisees
2022
France
evaluation of the transparency committee
epilepsy, generalized
Epilepsy
incomplete
Lamotrigine
Epilepsy
lamictal
generalized epilepsy, nos
lamotrigine
registries
epilepsies, partial

---
https://www.cochrane.org/fr/CD013575/DEPRESSN_la-lamotrigine-dans-le-traitement-de-prevention-des-recidives-du-trouble-bipolaire
2021
United Kingdom
review of literature
french abstract
Bipolar disorder
Lamotrigine
preventive treatment, nos
lamotrigine
Bipolar disorders
bipolar disorder
bipolar disorder, nos
Bipolar disorders
recurrence

---
https://www.cochrane.org/fr/CD001909/EPILEPSY_lamotrigine-therapie-dappoint-pour-lepilepsie-focale-resistante-aux-medicaments
2020
false
true
false
France
United Kingdom
triazines
treatment outcome
review of literature
french abstract
drug resistance
epilepsies, partial
Lamotrigine

---
https://www.has-sante.fr/jcms/p_3148224/fr/lamictal
2020
false
false
false
France
Lamotrigine
evaluation of the transparency committee
lamictal

---
https://www.cochrane.org/fr/CD001031/la-lamotrigine-par-rapport-la-carbamazepine-en-monotherapie-traitement-avec-un-seul-medicament-pour
2018
false
false
false
false
France
United Kingdom
French
review of literature
comparative effectiveness research
Evidence-Based medicine
carbamazepine
anticonvulsants
anticonvulsants
carbamazepine
epilepsy
triazines
triazines
Lamotrigine
Lamotrigine

---
https://pharmacomedicale.org/medicaments/par-specialites/item/lamotrigine
2017
false
true
false
France
Lamotrigine
Lamotrigine
anticonvulsants
anticonvulsants
anticonvulsants
drug information
Lamotrigine

---
http://www.has-sante.fr/portail/display.jsp?id=c_556176
http://www.has-sante.fr/portail/jcms/c_1652822/fr/lamictal
http://www.has-sante.fr/portail/jcms/c_1652821/fr/lamictal-02102013-avis-ct12190
2013
France
French
tablets
anticonvulsants
triazines
administration, oral
adult
adolescent
epilepsy, generalized
epilepsies, partial
drug therapy, combination
insurance, health, reimbursement
lamotrigine
evaluation of the transparency committee
bipolar disorder
depressive disorder
epileptic encephalopathy, Lennox-Gastaut type
intellectual disability
spasms, infantile
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69757422
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63999785
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62049762
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64374733
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67873093
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65263198
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65043661
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60650636
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65386749
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64681216
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62897973
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60659891
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67829684
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62578192
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65529193
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69967246
2012
France
summary of product characteristics
package leaflet
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63118161
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61065653
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65772003
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66897294
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69175678
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64776244
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61864408
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60487922
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69801840
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64755474
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69080600
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68403716
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63079979
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60355931
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67948731
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69356080
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65131079
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65503120
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61626015
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69377288
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60365295
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64109788
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69027590
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68484764
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69851010
2012
France
summary of product characteristics
package leaflet
tablets
Lamotrigine

---
http://www.lecrat.eu/?s=Lamotrigine
2012
France
French
pregnancy
triazines
anticonvulsants
infant, newborn
breast feeding
lamotrigine
triazines
drug information
Lamotrigine

---
http://www.cochrane.org/fr/CD006044
2011
false
false
United Kingdom
France
French
meta-analysis
acute pain
chronic pain
triazines
analgesics
treatment outcome
french abstract
Lamotrigine

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-06/lamictal_lamicstart_-_ct-7616.pdf
http://www.has-sante.fr/portail/jcms/c_957058/lamictal-lamicstart
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-04/lamictal_lamicstart_ct_7616.pdf
2010
France
French
English
depressive disorder
depressive disorder
treatment outcome
triazines
administration, oral
triazines
bipolar disorder
adult
insurance, health, reimbursement
triazines
evaluation of the transparency committee
Lamotrigine
Lamotrigine

---
http://www.cochrane.org/fr/CD007783
2010
false
true
false
France
United Kingdom
Refractory epilepsy (disorder)
triazines
treatment outcome
review of literature
french abstract
epilepsy, tonic-clonic
Lamotrigine

---
http://www.has-sante.fr/portail/jcms/c_957059/lamictal-lamicstart
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-06/lamictal_lamicstart_-_ct-8271.pdf
http://www.has-sante.fr/portail/jcms/c_990417/lamictal-/-lamicstart-lamotrigine-anti-epileptique
2010
France
French
administration, oral
adolescent
child
triazines
anticonvulsants
insurance, health, reimbursement
epilepsy, absence
treatment outcome
triazines
anticonvulsants
lamotrigine
triazines
evaluation of the transparency committee
guidelines for drug use
Lamotrigine
Lamotrigine

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-06/lamictal_lamicstart_-_ct-7616.pdf
http://www.has-sante.fr/portail/jcms/c_990403/lamictal-/-lamicstart-lamotrigine-psychotrope
2010
France
French
administration, oral
bipolar disorder
insurance, health, reimbursement
adult
depressive disorder
antimanic agents
treatment outcome
triazines
triazines
antimanic agents
guidelines for drug use
evaluation of the transparency committee
Lamotrigine
Lamotrigine

---
http://www.lecrat.eu/?s=Donn%C3%A9es+r%C3%A9centes+sur+lamotrigine+et+malformations
2009
France
French
calcium channel blockers
anticonvulsants
triazines
pregnancy
abnormalities, drug-induced
cleft lip
cleft palate
lamotrigine
triazines
drug information
Lamotrigine

---
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Lamotrigine.aspx
2009
false
Canada
French
English
child
triazines
triazines
anticonvulsants
anticonvulsants
triazines
administration, oral
lamotrigine
drug information
patient education handout
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69352363
2008
France
French
tablets
anticonvulsants
triazines
triazines
anticonvulsants
administration, oral
epilepsy
adult
child
adolescent
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
drug approval
lamotrigine
triazines
package leaflet
summary of product characteristics
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66584709
2008
France
French
tablets
anticonvulsants
triazines
triazines
administration, oral
adult
child
drug therapy, combination
epilepsy
adolescent
aged
drug approval
pregnancy
breast feeding
anticonvulsants
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69658075
2008
France
French
calcium channel blockers
anticonvulsants
triazines
triazines
tablets
administration, oral
anticonvulsants
epilepsy
drug therapy, combination
adult
adolescent
child
aged
drug approval
drug labeling
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61043653
2008
France
French
calcium channel blockers
anticonvulsants
triazines
anticonvulsants
tablets
triazines
administration, oral
epilepsy
drug therapy, combination
adult
adolescent
child
aged
drug approval
drug labeling
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65667034
2008
France
French
calcium channel blockers
anticonvulsants
triazines
anticonvulsants
tablets
administration, oral
triazines
epilepsy
drug therapy, combination
adult
child
adolescent
aged
drug approval
drug labeling
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68080063
2008
France
French
child
adolescent
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
calcium channel blockers
anticonvulsants
triazines
anticonvulsants
tablets
administration, oral
triazines
drug approval
drug labeling
epilepsy
drug therapy, combination
adult
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68058063
2008
France
French
tablets
calcium channel blockers
anticonvulsants
triazines
administration, oral
anticonvulsants
triazines
drug approval
drug labeling
epilepsy
drug therapy, combination
adult
adolescent
child
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67326619
2008
France
French
tablets
anticonvulsants
triazines
administration, oral
triazines
anticonvulsants
adult
adolescent
epilepsy
drug therapy, combination
drug approval
drug labeling
child
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
lamotrigine
triazines
summary of product characteristics
package leaflet
Lamotrigine
Lamotrigine

---
http://www.has-sante.fr/portail/display.jsp?id=c_399433
2002
France
French
anticonvulsants
triazines
administration, oral
insurance, health, reimbursement
tablets
adult
adolescent
child
epilepsy, generalized
epilepsies, partial
drug therapy, combination
lamotrigine
triazines
evaluation of the transparency committee
Lamotrigine

---
http://www.has-sante.fr/portail/display.jsp?id=c_398982
2001
France
French
anticonvulsants
triazines
administration, oral
insurance, health, reimbursement
tablets
drug therapy, combination
adult
adolescent
child
epilepsy, generalized
epilepsies, partial
lamotrigine
triazines
evaluation of the transparency committee
Lamotrigine

---
http://www.has-sante.fr/portail/display.jsp?id=c_398983
2001
France
French
triazines
administration, oral
insurance, health, reimbursement
tablets
anticonvulsants
epilepsy, generalized
epilepsies, partial
drug therapy, combination
adult
adolescent
lamotrigine
triazines
evaluation of the transparency committee
Lamotrigine

---
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