Preferred Label : Ado-Trastuzumab Emtansine;

MeSH definition : Immunotoxin that consists of humanized monoclonal anti-HER2 antibody TRASTUZUMAB covalently linked to anti-microtubule agent MAYTANSINOID DM1 for treatment of metastatic breast cancer in patients who previously received trastuzumab and a TAXANES, separately or in combination.;

MeSH synonym : Ado Trastuzumab Emtansine; Trastuzumab Emtansine;

MeSH hyponym : huN901 DM1; huN901DM1; Trastuzumab DM1 Conjugate; Trastuzumab-DM1; Trastuzumab DM1;

Wikipedia link : https://en.wikipedia.org/wiki/Ado-trastuzumab emtansine;

UNII : SE2KH7T06F;

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Immunotoxin that consists of humanized monoclonal anti-HER2 antibody TRASTUZUMAB covalently linked to anti-microtubule agent MAYTANSINOID DM1 for treatment of metastatic breast cancer in patients who previously received trastuzumab and a TAXANES, separately or in combination.

https://www.has-sante.fr/jcms/p_3188463/fr/kadcyla
2020
false
false
false
France
chemotherapy, adjuvant
insurance, health, reimbursement
adult
treatment outcome
breast neoplasms
Early-Stage HER2 Positive Breast Cancer
receptor, erbB-2
infusions, intravenous
neoplasm, residual
trastuzumab emtansine
antineoplastic agents
Ado-Trastuzumab Emtansine
evaluation of the transparency committee

---
https://www.ansm.sante.fr/actualites/cancer-du-sein-lansm-met-a-disposition-deux-nouveaux-traitements-innovants
2019
false
false
false
France
French
drug information
innovative therapies
atezolizumab
antineoplastic agents
Ado-Trastuzumab Emtansine
breast neoplasms
therapies, investigational

---
http://www.has-sante.fr/portail/jcms/c_1735595/fr/kadcyla-trastuzumab-emtansine-anticorps-ciblant-le-recepteur-her-2-couple-a-un-cytotoxique
2014
false
France
French
trastuzumab emtansine
breast neoplasms
neoplasm metastasis
antineoplastic agents
receptor, erbB-2
infusions, intravenous
tubulin modulators
tubulin modulators
antineoplastic agents
adult
guidelines for drug use
evaluation of the transparency committee
Progression-Free survival
disease-free survival
survival analysis
treatment outcome
Locally advanced breast cancer
HER2 positive breast cancer
Ado-Trastuzumab Emtansine
Ado-Trastuzumab Emtansine

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00225
2014
false
false
false
Canada
drug information
trastuzumab emtansine
Ado-Trastuzumab Emtansine
kadcyla

---
https://pgtmsite.files.wordpress.com/2024/01/trastuzumab-emtansine_position-preliminaire_final-27oct2014.pdf
2014
Canada
drug information
Metastatic Malignant Neoplasm in the Breast
trastuzumab
neoplasm, malignant
HER2/Neu Positive
HER2-Positive Breast Carcinoma
breast neoplasms
trastuzumab emtansine
Trastuzumab Emtansine
HER-2 positive breast cancer
Ado-Trastuzumab Emtansine
Breast Cancer Therapeutic Procedure
breast cancer

---
http://www.has-sante.fr/portail/jcms/c_1735595/fr/kadcyla
2014
false
France
French
evaluation of the transparency committee
trastuzumab emtansine
infusions, intravenous
antineoplastic agents
antineoplastic agents
adult
breast neoplasms
neoplasm metastasis
receptor, erbB-2
treatment outcome
survival analysis
guidelines for drug use
Ado-Trastuzumab Emtansine
Ado-Trastuzumab Emtansine

---
https://www.ema.europa.eu/medicines/human/EPAR/Kadcyla
2013
false
United Kingdom
French
English
adult
breast neoplasms
neoplasm metastasis
drug approval
treatment outcome
europe
antineoplastic agents
antineoplastic agents
infusions, intravenous
HER2 positive breast cancer
drug evaluation
package leaflet
summary of product characteristics
syndication feed
receptor, erbB-2
continuity of patient care
tubulin modulators
tubulin modulators
survival analysis
drug monitoring
product surveillance, postmarketing
medication errors
drug interactions
pregnancy
contraception
breast feeding
clinical trials as topic
drug evaluation, preclinical
drug compounding
trastuzumab emtansine
Ado-Trastuzumab Emtansine
Ado-Trastuzumab Emtansine
Advanced cancer

---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/36173a-fra.php
2013
false
Canada
French
English
trastuzumab emtansine
Ado-Trastuzumab Emtansine
medication errors
breast neoplasms
neoplasm metastasis
antineoplastic agents
trastuzumab
pharmacovigilance note

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04/05/2025


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