HER2-Positive Breast Carcinoma

Preferred Label : HER2-Positive Breast Carcinoma;

NCIt synonyms : ERBB2 Overexpressing Subtype of Invasive Breast Carcinoma; ERBB2 Overexpressing Subtype of Breast Carcinoma; HER2 Overexpressing Breast Carcinoma; HER2 Overexpressing Subtype of Breast Carcinoma; HER2 Positive Breast Cancer; HER2 Positive Breast Carcinoma;

NCIt definition : A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER).;

Neoplastic status : Malignant;

Details

Origin ID

C53556;

UMLS CUI

C1960398;

Currated CISMeF NLP mapping
- HER-2 positive breast cancer [CISMeF Querying Strategy]
- HER2 positive breast cancer [MedDRA Preferred Term]
- HER2 positive breast cancer [Disease (Nov.)]
- Human epidermal growth factor 2 positive carcinoma of breast (disorder) [SNOMED CT concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Manual BTNT mappings - CISMeF
- Early-Stage HER2 Positive Breast Cancer [Indication]
- breast cancer whose tumours overexpress HER2 with hormone receptor-negative metastatic disease that has progressed [Indication]
Protocole(s) indiqué(s)
- Capecitabine/Lapatinib Regimen [NCIt concept]
- Lapatinib/Trastuzumab Regimen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- HER2 positive breast cancer [Disease (Nov.)]
- HER2 positive breast cancer [MedDRA Preferred Term]
- Human epidermal growth factor 2 positive carcinoma of breast (disorder) [SNOMED CT concept]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- AC-T-T Regimen [NCIt concept]
- PCH Regimen [NCIt concept]
- TCH Regimen [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- c-erbB2 Messenger RNA Overexpression [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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