Aprepitant - CISMeF

Preferred Label : Aprepitant;

MeSH definition : A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.;

MeSH hyponym : MK 0869; MK-0869; MK0869; MK-869; MK869; MK0517; MK-0517; L-754030; L754030; L 754,030; L-754,030; L754,030;

MeSH CAS label : 3H-1,2,4-Triazol-3-one, 5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,4-dihydro-;

Wikipedia link : https://en.wikipedia.org/wiki/Aprepitant;

UNII : 1NF15YR6UY;

Details

Origin ID

D000077608;

UMLS CUI

C1176306;

ATC code(s)
- aprepitant [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fosaprepitant [NCIt concept]
- Fosaprepitant (substance) [SNOMED CT concept]
- Fosaprepitant Dimeglumine [NCIt concept]
- Fosaprepitant dimeglumine (substance) [SNOMED CT concept]
- Product containing fosaprepitant (medicinal product) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Aprepitant [NCIt concept]
- Aprepitant [ICD-11 Extension code]
- Aprepitant [SMS substance]
- Aprepitant (substance) [SNOMED CT concept]
- aprepitant [Substance BNPC]
MeSH indexing information
- antidepressive agents [MeSH Descriptor]
- receptors, neurokinin-1 [MeSH Descriptor]
Pharmacological action(s)
- Neurokinin-1 receptor antagonists [MeSH Descriptor]
- antiemetics [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
Record concept(s)
- (1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine [MeSH concept]
- (2R)-(1R)-3,5-bis(Trifluoromethylphenyl)ethoxy)-(3S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazole)methyl-morpholine [MeSH concept]
- L 754030 [MeSH concept]
- MK 0517 [MeSH concept]
- MK 869 [MeSH concept]
- aprepitant [MeSH concept]
- emend [MeSH concept]
See also inter- (CISMeF)
- Product containing aprepitant (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- aprepitant [ATC Code]

Keyword's position in hierarchy(ies) :

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