prodrugs - CISMeF

Preferred Label : prodrugs;

Obsolete resource : false;

MeSH definition : A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.;

MeSH synonym : precursors, drug; pro-drugs; pro drugs; drug precursors; Drug Precursor; Precursor, Drug; Prodrug; Pro-Drug; Pro Drug;

MeSH annotation : a cpd that on admin must undergo chem conversion by metab processes before becoming the pharmacologically active drug for which it is a prodrug; D25-26 qualif; coord IM with specific drug (IM); coordinate with specific drug;

Wikipedia link : https://en.wikipedia.org/wiki/Prodrug;

action pharmacologique : O;

Details

Origin ID

D011355;

UMLS CUI

C0033262;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
Indexing information
- ((O,O-diacetyl)-L-dopa-methylester)succinyldiamide [MeSH Supplementary Concept]
- (1-(chloromethyl)-1,2-dihydropyrrolo(3,2-e)indol-3(6H)-yl)(5-fluoro-1H-indol-2-yl)methanone [MeSH Supplementary Concept]
- (5-chloro-1H-indol-2-yl)(1-(chloromethyl)-1,2-dihydropyrrolo(3,2-e)indol-3(6H)-yl)methanone [MeSH Supplementary Concept]
- 2-((3'-(4-chloro-2,5-dimethylphenylsulfonylamino)-3,5-dimethylbiphenyl-4-carbonyl)methylamino)-4-dimethylaminobutyric acid methyl ester [MeSH Supplementary Concept]
- 2-amino-N-(2-methyl-5-(1-(4-sulfamoylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)phenyl)acetamide hydrochloride [MeSH Supplementary Concept]
- 3'-azido-3'-deoxythymidine-5'-bis(3,3-diacetoxy-propyl)phosphate [MeSH Supplementary Concept]
- 5-Fluoroindole-3-acetic acid [MeSH Supplementary Concept]
- 5-fluoropyrimidin-2-one [MeSH Supplementary Concept]
- A-322278 [MeSH Supplementary Concept]
- AVE 7688 [MeSH Supplementary Concept]
- AWO54 [MeSH Supplementary Concept]
- BIBR 953 [MeSH Supplementary Concept]
- BP-PM279G [MeSH Supplementary Concept]
- BP-PM6 [MeSH Supplementary Concept]
- DB868 compound [MeSH Supplementary Concept]
- DG17 compound [MeSH Supplementary Concept]
- DTS-108 [MeSH Supplementary Concept]
- EM 800 [MeSH Supplementary Concept]
- FV-100 [MeSH Supplementary Concept]
- Famciclovir [MeSH Descriptor]
- HX0507 [MeSH Supplementary Concept]
- HX0969 [MeSH Supplementary Concept]
- HY023016 [MeSH Supplementary Concept]
- ICF05016 [MeSH Supplementary Concept]
- IDX184 [MeSH Supplementary Concept]
- IMD-1041 [MeSH Supplementary Concept]
- Irinotecan [MeSH Descriptor]
- L 377202 [MeSH Supplementary Concept]
- LEG-3 prodrug [MeSH Supplementary Concept]
- N'-(1-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyloxy)phenyl)ethylidene)isonicotinohydrazide [MeSH Supplementary Concept]
- N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide [MeSH Supplementary Concept]
- N-(3-((6-chlorothiazolo(5,4-b)pyridin-2-yl)methoxy)-2,6-difluorobenzoyl)-1-methylpiperidine-4-carboxamide [MeSH Supplementary Concept]
- Phe-Ala-PQ [MeSH Supplementary Concept]
- RB 101 [MeSH Supplementary Concept]
- RB 6145 [MeSH Supplementary Concept]
- S 1108 [MeSH Supplementary Concept]
- SN 28343 [MeSH Supplementary Concept]
- Temozolomide [MeSH Descriptor]
- UNIL088 [MeSH Supplementary Concept]
- Valacyclovir [MeSH Descriptor]
- WR319670 [MeSH Supplementary Concept]
- balsalazide [MeSH Supplementary Concept]
- bambuterol [MeSH Supplementary Concept]
- bispivaloylthioethyl zidovudine monophosphate [MeSH Supplementary Concept]
- candoxatril [MeSH Supplementary Concept]
- chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate [MeSH Supplementary Concept]
- desciclovir [MeSH Supplementary Concept]
- diethylenetriamine pentaacetic acid penta-ethyl ester [MeSH Supplementary Concept]
- dimethylaminomicheliolide [MeSH Supplementary Concept]
- dipivalyl terbutalone [MeSH Supplementary Concept]
- docarpamine [MeSH Supplementary Concept]
- dodecyl nicotinate [MeSH Supplementary Concept]
- erythromycin 2'-acetate [MeSH Supplementary Concept]
- fluphenazine depot [MeSH Supplementary Concept]
- fosinoprilat [MeSH Supplementary Concept]
- fosphenytoin [MeSH Supplementary Concept]
- glycine-valine-saquinavir [MeSH Supplementary Concept]
- glycyrrhizic acid diethyl ester [MeSH Supplementary Concept]
- hydroxymethylnitrofurazone [MeSH Supplementary Concept]
- isoleucine-quinidine conjugate [MeSH Supplementary Concept]
- isosorbide-5-nicotinate-2-aspirinate [MeSH Supplementary Concept]
- melflufen [MeSH Supplementary Concept]
- nalbuphine pivalate [MeSH Supplementary Concept]
- poly(vanillin oxalate) [MeSH Supplementary Concept]
- prednisolone acetate [MeSH Supplementary Concept]
- propacetamol [MeSH Supplementary Concept]
- remdesivir [MeSH Supplementary Concept]
- retinoyl glutamate [MeSH Supplementary Concept]
- selexipag [MeSH Supplementary Concept]
- sibrafiban [MeSH Supplementary Concept]
- tazarotene [MeSH Supplementary Concept]
- tretazicar [MeSH Supplementary Concept]
- valdecitabine [MeSH Supplementary Concept]
- valine-valine-saquinavir [MeSH Supplementary Concept]
Record concept(s)
- prodrugs [MeSH concept]
Related MeSH Supplementary Concept(s)
- 17beta-dihydroxyestra-1,4-dien-3-one [MeSH Supplementary Concept]
- AT-752 [MeSH Supplementary Concept]
- BFE1224 [MeSH Supplementary Concept]
- CJ(2) [MeSH Supplementary Concept]
- CX-2029 [MeSH Supplementary Concept]
- TXA709 [MeSH Supplementary Concept]
- pradefovir [MeSH Supplementary Concept]
Semantic type(s)
- Chemical Viewed Functionally [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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