fosinoprilat - CISMeF

Preferred Label : fosinoprilat;

MeSH note : active phosphinic acid metabolite of prodrug fosenopril, which is activated by esterases in vivo; structure given in first source; binds zinc with phosphinic acid group;

CISMeF synonym : SQ 27519; fosfenopril;

MeSH synonym : fosinoprilic acid;

MeSH hyponym : SQ-27519; SQ-27,519;

MeSH CAS label : L-Proline, 4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-, trans-;

MeSH Related Number : 95399-71-6 (fosinoprilic acid);

Registry Number MeSH : 95399-71-6;

Is substance : O;

UNII : S312EY6ZT8;

InChIKey : WOIWWYDXDVSWAZ-RTWAWAEBSA-N;

Details

Origin ID

C046965;

UMLS CUI

C0075061;

Automatic exact mappings (from CISMeF team)
- Fosinoprilat [NCIt concept]
MeSH indexing information
- prodrugs [MeSH Descriptor]
MeSH term(s) associated for indexing
- fosinopril [MeSH Descriptor]
Pharmacological action(s)
- angiotensin-converting enzyme inhibitors [MeSH Descriptor]
- anti-arrhythmia agents [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
Record concept(s)
- SQ 27519 [MeSH concept]
- fosfenopril [MeSH concept]
- fosinoprilat [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fosinoprilat [NCIt concept]

Keyword's position in hierarchy(ies) :

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