balsalazide - CISMeF

Preferred Label : balsalazide;

MeSH note : a mesalamine 5-aminosalicylate prodrug; 99% of ingested drug remains intact through the stomach and is delivered to and activated in the colon; used for inflammatory bowel disease, ulcerative colitis and radiation-induced proctosigmoiditis but avoided in patients with known hypersensitivity reaction to salicylates or mesalamine; structure in first source;

CISMeF synonym : BX 661A; balsalazide disodium; balsalazine; colazal; colazide; salix brand of balsalazide disodium; shire brand of balsalazide disodium;

MeSH synonym : 5-(carboxyethylcarbamoyl-4-phenylazo)salicylic acid;

MeSH hyponym : BX661A;

MeSH CAS label : benzoic acid, 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, disodium salt;

MeSH Related Number : 82101-18-6 (balsalazide);

Registry Number MeSH : 82101-18-6;

Is substance : O;

UNII : P80AL8J7ZP;

InChIKey : IPOKCKJONYRRHP-FMQUCBEESA-N;

Details

Origin ID

C038637;

UMLS CUI

C0052940;

ATC code(s)
- balsalazide [ATC Code]
Currated CISMeF NLP mapping
- Balsalazide [NCIt concept]
- Balsalazide (substance) [SNOMED CT concept]
- Product containing balsalazide (medicinal product) [SNOMED CT concept]
MeSH indexing information
- colitis, ulcerative [MeSH Descriptor]
- inflammatory bowel diseases [MeSH Descriptor]
- prodrugs [MeSH Descriptor]
MeSH term(s) associated for indexing
- mesalamine [MeSH Descriptor]
- phenylhydrazines [MeSH Descriptor]
Pharmacological action(s)
- anti-inflammatory agents, non-steroidal [MeSH Descriptor]
- gastrointestinal agents [MeSH Descriptor]
Record concept(s)
- BX 661A [MeSH concept]
- balsalazide [MeSH concept]
- balsalazide disodium [MeSH concept]
- balsalazine [MeSH concept]
- colazal [MeSH concept]
- colazide [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Balsalazide [NCIt concept]
- Balsalazide (substance) [SNOMED CT concept]
- Product containing balsalazide (medicinal product) [SNOMED CT concept]
- balsalazide [ATC Code]
Validated automatic mappings to BTNT
- Balsalazide disodium (substance) [SNOMED CT concept]
- balsalazide [ATC Code]

Keyword's position in hierarchy(ies) :

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