receptors, neurokinin-1

Preferred Label : receptors, neurokinin-1;

MeSH definition : A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.;

MeSH synonym : neurokinin-1 receptor; sp p receptor; receptor, nk-1; nk 1 receptors; substance p receptors; nk-1 receptor; p receptors, substance; neurokinin 1 receptor; sp-p receptor; neurokinin-1 receptors; nk-1 receptors; sp p receptors; substance p receptor; nk 1 receptor; receptors, nk-1; receptors, nk 1; sp-p receptors; receptor, neurokinin-1; neurokinin 1 receptors; receptors, sp-p; receptors, sp p; receptor, sp-p; p receptor, substance; receptor, substance p; receptors, substance p; receptors, neurokinin 1; tachykinin receptor 1; Substance-P receptor; receptor, Substance-P;

MeSH annotation : tachykinin receptors; DF: RECEPT NEUROKININ 1;

Wikipedia link : https://en.wikipedia.org/wiki/Tachykinin receptor 1;

Is substance : O;

Details

Origin ID

D018040;

UMLS CUI

C0164209;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- Substance-P Receptor [NCIt concept]
Indexing information
- 1-(4-(3,5-bis(trifluoromethyl)benzyloxymethyl)-4-phenylpiperidin-1-yl)-2-pyrrolidineacetamide [MeSH Supplementary Concept]
- 1-(5-((2-((1-(3,5-bis(trifluoromethyl)phenyl)ethyl)oxy)-3-(4-fluorophenyl)morpholin-4-yl)methyl)-2H-1,2,3-triazol-4-yl)-N,N-dimethylmethanamine [MeSH Supplementary Concept]
- 1-(amino(oxo)acetyl)-N-(1-(3,5-bis(trifluoromethyl)phenyl)ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide [MeSH Supplementary Concept]
- 1-oxo-7-azaspirodecane [MeSH Supplementary Concept]
- 2-(1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluoro)phenyl-4-(5-(2-phosphoryl-3-oxo-4H,-1,2,4-triazolo))methylmorpholine, bis(N-methylglucamine) salt [MeSH Supplementary Concept]
- 2-piperazin-1-ylindan-2-carboxylic acid (3-chloro-5-fluorobenzyl)methylamide [MeSH Supplementary Concept]
- 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-1-methyl-2-phenylpiperidine [MeSH Supplementary Concept]
- 3-(6-methoxy-1-methyl-1-trifluoromethylisochroman-7-yl)methylamino-2-phenylpiperidine [MeSH Supplementary Concept]
- 3-aryl-6-phenyl-1-oxa-7-azaspiro(4.5)decane [MeSH Supplementary Concept]
- 4-(3,5-bis(trifluoromethyl)benzyloxymethyl)-1-(2-methylthiazol-5-ylmethyl)-4-phenylpiperidine [MeSH Supplementary Concept]
- 6-phenyl-1-oxa-7-azaspiro(4,5)decane [MeSH Supplementary Concept]
- ASN 1377642 [MeSH Supplementary Concept]
- AZD 2738 [MeSH Supplementary Concept]
- AZD 8081 [MeSH Supplementary Concept]
- Aprepitant [MeSH Descriptor]
- CAM 4515 [MeSH Supplementary Concept]
- CAM 4750 [MeSH Supplementary Concept]
- CI 1021 [MeSH Supplementary Concept]
- CJ 11974 [MeSH Supplementary Concept]
- FK886 [MeSH Supplementary Concept]
- HSP 117 [MeSH Supplementary Concept]
- L 741671 [MeSH Supplementary Concept]
- L 743310 [MeSH Supplementary Concept]
- LY 306740 [MeSH Supplementary Concept]
- MDL 103392 [MeSH Supplementary Concept]
- MDL 105212A [MeSH Supplementary Concept]
- MDL 108,207DA [MeSH Supplementary Concept]
- MEN 10930 [MeSH Supplementary Concept]
- N-(1-(3,5-bis(trifluoromethyl)phenyl)ethyl)-7,8-dihydro-N,7-dimethyl-5-(4-methylphenyl)-8-oxo-1,7-naphthyridine-6-carboxamide [MeSH Supplementary Concept]
- N-(3,5-bis(trifluoromethyl)benzyl)-7,8-dihydro-N,7-dimethyl-5-(4-methylphenyl)-8-oxo-1,7-naphthyridine-6-carboxamide [MeSH Supplementary Concept]
- PD 174424 [MeSH Supplementary Concept]
- S 16474 [MeSH Supplementary Concept]
- S 18523 [MeSH Supplementary Concept]
- SDZ NKT 343 [MeSH Supplementary Concept]
- YM 35375 [MeSH Supplementary Concept]
- cyclo((2-naphthyl)alanyl-tryptophyl-(4-fluoro)phenylalanyl-threonyl-phenylalanyl-prolyl) [MeSH Supplementary Concept]
- ezlopitant [MeSH Supplementary Concept]
- rolapitant [MeSH Supplementary Concept]
- sch 425078 [MeSH Supplementary Concept]
- serlopitant [MeSH Supplementary Concept]
- substance P (5-11), Glp(5)-Glu(O-benzyl)(11)- [MeSH Supplementary Concept]
- substance P (6-11), Glp(6)-Glu(O-benzyl)(11)- [MeSH Supplementary Concept]
- substance P, Arg(1)-Pro(2)-Phe(7)-His(9)- [MeSH Supplementary Concept]
- substance P, Cys(3,6)-Tyr(8)-Pro(9)- [MeSH Supplementary Concept]
- tyrosyl-alanyl-glycyl-phenylalanyl-methionyl-prolyl-leucyl-tryptophyl-O-3,5-benzyl(CF3)2 [MeSH Supplementary Concept]
- tyrosyl-alanyl-glycyl-phenylalanyl-norleucyl-prolyl-leucyl-tryptophyl-O-3,5-benzyl(CF3)2 [MeSH Supplementary Concept]
- tyrosyl-cyclo(penicillamine-glycyl-phenylalanyl-penicillamine)-prolyl-leucyl-tryptophyl-NH-(3',5'-(CF3)2-Bzl) [MeSH Supplementary Concept]
Record concept(s)
- receptors, Neurokinin-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TACR1 protein, human [MeSH Supplementary Concept]
Related MeSH term(s)
- Neurokinin-1 receptor antagonists [MeSH Descriptor]
See also
- substance P [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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