Preferred Label : rolapitant;
MeSH note : an anti-emetic agent; structure in first source;
CISMeF synonym : SCH 619734; 8-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4,5)decan-2-one;
MeSH synonym : (5S,8S)-8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4.5)decan-2-one;
MeSH hyponym : (5S,8S)-8-(((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4.5)decan-2-one;
Is substance : O;
UNII : NLE429IZUC;
Origin ID : C578834;
UMLS CUI : C3273719;
ATC code(s)
Currated CISMeF NLP mapping
MeSH indexing information
MeSH term(s) associated for indexing
Pharmacological action(s)
Record concept(s)
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
https://www.has-sante.fr/portail/jcms/c_2801854/fr/varuby-rolapitant-antiemetique-antagoniste-des-recepteurs-nk1
https://www.has-sante.fr/portail/jcms/c_2801854/fr/varuby
2017
false
false
false
France
French
rolapitant
rolapitant
treatment outcome
nausea
vomiting
nausea
vomiting
antineoplastic agents
drug therapy, combination
administration, oral
Neurokinin-1 receptor antagonists
Neurokinin-1 receptor antagonists
adult
antiemetics
antiemetics
guidelines for drug use
evaluation of the transparency committee
insurance, health, reimbursement
dexamethasone
serotonin 5-HT3 receptor antagonists
rolapitant
rolapitant
rolapitant
spiro compounds
spiro compounds
---
https://www.ema.europa.eu/medicines/human/EPAR/Varuby
2017
false
false
false
United Kingdom
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
rolapitant
rolapitant
drug approval
europe
treatment outcome
nausea
vomiting
nausea
vomiting
antineoplastic agents
drug therapy, combination
administration, oral
Neurokinin-1 receptor antagonists
Neurokinin-1 receptor antagonists
product surveillance, postmarketing
adult
pregnancy
breast feeding
antiemetics
antiemetics
drug evaluation, preclinical
rolapitant
spiro compounds
rolapitant
rolapitant
spiro compounds
spiro compounds
---