Rho Guanine Nucleotide Exchange Factor 28

Preferred Label : Rho Guanine Nucleotide Exchange Factor 28;

NCIt synonyms : 190 kDa Guanine Nucleotide Exchange Factor; p190RhoGEF; Rho-Interacting Protein 2; Rho-Guanine Nucleotide Exchange Factor; Rho Guanine Nucleotide Exchange Factor; Rho Interacting Protein 2; P190-RhoGEF; ARHGEF28;

NCIt definition : Rho guanine nucleotide exchange factor 28 (1705 aa, 192 kDa) is encoded by the human ARHGEF28 gene. This protein plays a role in the mediation of guanine nucleotide exchange for the GTPase transforming protein Rho A.;

Details

Origin ID

C97267;

UMLS CUI

C2935655;

OMIM relation
- Rho guanine nucleotide exchange factor 28 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ARHGEF28 protein, human [MeSH concept]
- ARHGEF28 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ARHGEF28 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- DAG/PE-Binding Domain [NCIt concept]
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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