NCIt definition : A regimen consisting of five phases used for the treatment of adult L3 acute lymphoblastic
leukemia (ALL3 or Burkitt's type) and for adult Burkitt's lymphoma. The five phases
include: cytoreduction, induction given as two consecutive courses, consolidation
and maintenance. This particular regimen differs from other LMB/SFOP (B-cell non-Hodgkin
lymphoma and B-ALL/Societe Francaise Oncologie Pediatrique) protocols to reflect the
treatment of central nervous system (CNS) disease using high dose methotrexate, high
dose cytarabine, intrathecal therapy and cranial irradiation. The LMB 89 Group C regimen
follows a similar regimen to that outlined in the LMB 86 protocol.;
Semantic type(s)