IRS1 wt Allele

Preferred Label : IRS1 wt Allele;

NCIt synonyms : Insulin Receptor Substrate 1 wt Allele; HIRS-1;

NCIt definition : Human IRS1 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes insulin receptor substrate 1 protein, is involved in the progression of signaling from both insulin and cytokine-responsive receptors.;

GenBank Accession Number : NM_005544;

Détails

Origin ID

C52397;

UMLS CUI

C1704984;

OMIM relation
- Insulin receptor substrate 1 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Diabetes Mellitus [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 2: 227489980-227425443 [NCIt concept]
gene_in_chromosomal_location
- 2q36 [NCIt concept]
gene_is_element_in_pathway
- Growth Hormone Signaling Pathway [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IGF1R Antiapoptosis Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL4 Signaling Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
gene_plays_role_in_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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