Zinc Finger Protein SNAI2

Preferred Label : Zinc Finger Protein SNAI2;

NCIt synonyms : Neural Crest Transcription Factor Slug; SNAI2 Protein; Snail Homolog 2 Protein; Protein Snail Homolog 2; SNAI2;

NCIt definition : Zinc finger protein SNAI2 (268 aa, 30 kDa) is encoded by the human SNAI2 gene. This embryonic transcription factor functions as a transcriptional repressor. The protein has been implicated in the metastasis of several cancers.;

Détails

Origin ID

C50880;

UMLS CUI

C1709990;

OMIM relation
- Snail family transcriptional repressor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SNAI2 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
gene_product_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Hippo Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Organism Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]
is_target
- Synthetic Plumbagin PCUR-101 [NCIt concept]

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