Epidermal Growth Factor Receptor Pathway Substrate 15

Preferred Label : Epidermal Growth Factor Receptor Pathway Substrate 15;

NCIt synonyms : Protein EPS15; AF-1p Protein; EPS15; Epidermal Growth Factor Receptor Pathway Substrate-15; EGF Receptor Pathway Substrate-15; Protein AF-1p;

NCIt definition : Epidermal growth factor receptor substrate 15 (896 aa, 99 kDa) is encoded by the human EPS15 gene. This protein is involved in the internalization of epidermal growth factor receptor and in clathrin-coated pit formation.;

Details

Origin ID

C26179;

UMLS CUI

C1451891;

OMIM relation
- Epidermal growth factor receptor pathway substrate 15 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EPS15 protein, human [MeSH Supplementary Concept]
- EPS15 protein, human [MeSH concept]
gene_encodes_gene_product
- EPS15 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Coated Pit [NCIt concept]
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
gene_product_is_element_in_pathway
- Endocytosis Pathway [NCIt concept]
- Synaptic Vesicle Endocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Endocytotic Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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