NCIt synonyms : Carcinoembryonic Antigen Family Protein; CEA Family Protein; CEA;
NCIt definition : A cancer-specific antigen associated with both tumors and the developing fetus. The
main use of this antigen is as a tumor marker, especially with respect to intestinal
cancers. Production of the antigen ceases shortly before birth, but may reappear in
people who develop certain types of cancer.;
Alternative definition : NCI-GLOSS: A substance that is sometimes found in an increased amount in the blood
of people who have certain cancers, other diseases, or who smoke. It is used as a
tumor marker for colorectal cancer.;
NCIt note : Members of the CEA family consist of a single N domain, with structural similarity
to the immunoglobulin variable domains, followed by a variable number of immunoglobulin
constant-like A and/or B domains. (OMIM); The term carcinoembryonic antigen (CEA) may refer to the CEA protein family but it
is sometimes used to refer to CEACAM5 (carcinoembryonic antigen-related cell adhesion
molecule 5) alone.;
Codes from synonyms : CDR0000357558; CDR0000046474;