Carcinoembryonic Antigen Peptide 1

Preferred Label : Carcinoembryonic Antigen Peptide 1;

NCIt synonyms : CEA Peptide 9-mer; Carcinoembryonic Peptide-1; Carcinoembryonic Antigen Peptide-1; CEA Peptide 1;

NCIt related terms : CAP-1; CEA peptide-1;

NCIt definition : A nine amino acid peptide fragment of carcinoembryonic antigen (CEA), a protein that is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung. Autologous vaccination with activated autologous dendritic cells (DC) or peripheral blood mononuclear cells (PBMC) which have been exposed to CEA peptide 1 in vitro may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing CEA, thereby inhibiting tumor growth. (NCI04);

Alternative definition : NCI-GLOSS: A small piece of a tumor marker called carcinoembryonic antigen (CEA). CEA may be found in the blood of people who have colon cancer, other types of cancer or diseases, or who smoke tobacco. Carcinoembryonic antigen peptide-1 is used to make a vaccine that may help stimulate the body's immune system to kill cancer cells.;

NSC code : 672683;

Codes from synonyms : CDR0000044380; CDR0000633287; CDR0000046148;

Details

Origin ID

C2414;

UMLS CUI

C0393002;

Automatic exact mappings (from CISMeF team)
- CAP1 [MeSH concept]
- CAP1-6D [MeSH Supplementary Concept]
- Cyclase-associated actin cytoskeleton regulatory protein 1 [OMIM gene]
- TNF receptor associated factor 3 [ORDO Gene]
- Tnf receptor-associated factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Carcinoembryonic Antigen [NCIt concept]
is_component_of_chemotherapy_regimen
- Carcinoembryonic Antigen Peptide 1/Hepatitis B Antigen Peptide [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients